Results 81 to 90 of about 49,448 (297)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Relationship between social media addiction and bodyweight

, 2023
Introduction and aim. Social media addiction is increasing rapidly due to the widespread use of smartphones and the availability of the internet. Also, social media addiction constitutes a risk factor for many physical and mental diseases.
Serdar Mercimekçi, Mercimekçi, Serdar, Altuntaş, Zeynep Sena, Aypak, Cenk, Tatar, Selim, Zeynep Sena Altuntaş, Cenk Aypak, Özdemir, Ayşe, Selim Tatar, Ayşe Özdemir   +9 more
core   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

The Role of Social Comparison and Online Social Support in Social Media Addiction Mediated by Self-Esteem and Loneliness

Introduction: The diversity of information on social media provides a ubiquitous possibility for social comparison. Online social comparisons have both detrimental and beneficial effects; besides lowering one’s self-esteem, heightening loneliness and ...
Kevin M. FITZPATRICK, Csaba HAMVAI, Hedvig KISS, Alice HARTMANN, Bettina F. PIKÓ   +4 more
core   +2 more sources

Social Media Addiction Scale for Adolescents: Validity and Reliability Study

Addicta: The Turkish Journal on Addictions, 2019
Nowadays, technology and Internet use has been increasing, and this increase brings along social, psychological, and physical problems. Social media addiction is one of the problems that arise from intensive Internet and technology use.
Mustafa Özgenel, Ömer Canpolat, Halil Ekşi   +2 more
doaj   +1 more source

A Qualitative Study on the Reasons for Social Media Addiction [PDF]

European Journal of Educational Research, 2018
<p style="text-align:justify">The aim of this study was to determine the causes of social media addiction of individuals, who define themselves as social media addicts, in a clearer and more concrete way. In order to achieve this aim, participants have been tested with an addiction test, and 25 university students who perceive themselves as ...
openaire   +3 more sources

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Facebook addiction: concerns, criticisms and recommendations

, 2012
This paper provides a brief critique of the ‘Facebook addiction’ research field in relation to the Bergen Facebook Addiction Scale developed by Andreaessen and colleagues (2012).
Griffiths, MD
core  

Examining the Relationship Between University Students' Social Media Usage Purposes and Social Media Addiction Levels

International Journal of Turkish Education Sciences
The widespread integration of social media platforms into daily life has led to increased attention on both the purposes of their use and the potential for addiction resulting from prolonged usage.
Bayram Gökbulut
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source