Results 91 to 100 of about 49,448 (297)

A Neurological Comparison Between Addiction to Social Media and Drug [PDF]

Taḥqīqāt-i ̒Ulūm-i Raftārī
Aim and Background: There are claims regarding the fact that the damages caused by using social media are rather similar to those caused by using drugs. Researchers think that although the behavioral symptoms and consequences of using drugs vary by type ...
somayeh Rasouli, Anahita Khorrami Banaraki, Seyed Hassan Hosseini Sarvari   +2 more
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Social appearance anxiety and body checking behavior in the relationship between social media addiction and depressive symptoms among college students

Frontiers in Psychiatry
BackgroundThe relationship between social media addiction and depressive symptoms has been extensively studied; however, the underlying mechanisms remain unexplored.
Xiaochen Wang, Yanan Wang, Shufei Yang, Zhen Li, Chang Fu   +4 more
doaj   +1 more source

Social Media Usage or Addiction: Social Media Addiction among Late Adolescence [PDF]

ATSK Journal of Psychology, 2020
Nazia Yaqoob, Shumaila Mehnaz, Ammarah Saleem   +2 more
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

The impact of social media addiction on self-esteem and life satisfaction among married couples

Journal of Family Medicine and Primary Care
Introduction: The pervasive use of social media has become an integral part of daily life, influencing various aspects of individual and relational well-being.
Lisa Chadha, Poonam Sharma, Rajwant Kaur, Inu Arya, Prashant Sharma   +4 more
doaj   +1 more source

Social media addiction is a new smoking

Annals of Psychophysiology, 2018
Background: Addiction is the behavior of a human in which they depend fully on the substance. According to the World Health Organization (WHO) 2015, over 1.1 billion people smoked tobacco whereas; over 2.14 billion people used social networks. The objective of this study is to assess that is there any similarity between the addiction level of smoking ...
Sonya Arshad, Muhammad Faisal Qureshi, Syed Hasan Abbas Rizvi, Bakhtawar Ferozali, Sidra Abdul Majeed, Summaya Khan, Haziq Ajaz   +6 more
openaire   +3 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source