Results 71 to 80 of about 49,448 (297)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
MaskanaAs social media use continues to expand, its potential effects on mental health have become a growing concern, especially for young adults who are among the most active users.
Iason Psiachos +2 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
, 2021 Social media use has become part of daily life for many people. Earlier research showed that problematic social media use is associated with psychological distress and relationship satisfaction.
Satici B., Kayis A.R., Griffiths M.D. +1 more
core +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
A Study on Social Media Addiction: The Roles of Personality, Internet Use, and Platform Preference
Düzce Tıp Fakültesi DergisiAim: This study aimed to determine the relative contributions of personality traits, internet addiction, and social media platform preferences to social media addiction, within the framework of the big five personality model.Material and Methods: Data ...
Ayşegül Barak +2 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The objective of this research is to explore the connections between preoccupation with healthy dietary habits, social physical apprehension, and addiction to social networking platforms among young people.
Merve Kişi, Selin Kalender
core +1 more source
Social media is a great place which provides opportunities of socialising with people all over the world, sharing special moments with others, promoting a business and earning money. But if people don’t use it with caution, it can become harmful and destroy people's lives.
Akstinaitė, Gabrielė +1 more
openaire +3 more sources