Results 111 to 120 of about 49,448 (297)

Investigation of the Risk of Social Media Addiction and Individual-Social Problems in Adolescents

Psikiyatride Güncel Yaklaşımlar
Objective: This study aimed to investigate the relationship between social media addiction and individual as well as social problems in adolescents. Method: A cross-sectional, relational design was employed from October 2020 to October 2021, involving ...
Damla Duman, Nazan Turan
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Representing Addiction in Contemporary Media [PDF]

openThis thesis explores the multifaceted representations of addiction in various media with the aim of shedding light on the complex socio-cultural implications of these representations.
CHMIELARCZYK, MILENA
core  

Internet gaming addiction - a systematic review of empirical research

, 2012
The activity of play has been ever present in human history and the Internet has emerged as a playground increasingly populated by gamers. Research suggests that a minority of Internet game players experience symptoms traditionally associated with ...
Kuss, DJ, Griffiths, MD
core   +1 more source

Online gaming addiction: the role of sensation seeking, self-control, neuroticism, aggression, state anxiety and trait anxiety [PDF]

, 2010
Research into online gaming has steadily increased over the last decade, although relatively little research has examined the relationship between online gaming addiction and personality factors.
Mehroof, M, Griffiths, MD, Mark D. Griffiths, Mehwash Mehroof   +3 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

The relationship between childhood psychological abuse and social media addiction among college students: the mediating role of fear of missing out and the moderating role of left-behind experience

Introduction Mobile social media is a new type of online media that is participatory, open, and communicative, among other characteristics. Due to the increasing popularity of social media, this technology has become an indispensable part of people’s ...
Hai-qin Yu, Peng-cheng Wei
core   +1 more source

Video game characteristics, happiness and flow as predictors of addiction among video game players: A pilot study.

, 2013
AIMS: Video games provide opportunities for positive psychological experiences such as flow-like phenomena during play and general happiness that could be associated with gaming achievements.
Williams, Glenn A., Hull, Damien C., Williams, GA, Griffiths, Mark D., Damien C. Hull, Griffiths, MD, Mark D. Griffiths, Glenn A. Williams, Hull, DC   +8 more
core   +1 more source

Addictive motivational scaffolds and the structure of social media

Synthese
Abstract In this paper, I propose an account of behavioral addiction in terms of what I call addictive motivational scaffolds (AMSs). Taking inspiration from recent work concerning psychiatric externalism and addiction, I propose and describe the concept of motivational scaffolding: external structure that ...
openaire   +3 more sources