Results 51 to 60 of about 1,282,524 (305)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Revenue Sources and Social Media Engagement Among Environmentally Focused Nonprofits

Journal of Public and Nonprofit Affairs, 2017
This study examines social media efforts among environmentally focused nonprofits. A survey of environmentally focused nonprofits revealed that more than half of these organizations receive government funding.
John R. McCaskill, James R. Harrington
doaj   +1 more source

Fostering Dialogic Engagement: Toward an Architecture of Social Media for Social Change

Social Media + Society, 2021
Dialogic theory and engagement hold great potential as frameworks for thinking about how social media can facilitate public discussions about social issues.
Michael L. Kent, Maureen Taylor
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

The impact of social media overload on learning engagement: a moderated mediation model

BMC Psychology
This research aims to investigate the mechanisms through which social media overload affects learning engagement among university students. A moderated mediation model was constructed to examine the mediating role of ego depletion between social media ...
Ninggui Duan, Lina Li, Kessara Kanchanapoom, Zhou Qi, Tongfeng Xu   +4 more
doaj   +1 more source

Effect of Social Media Marketing on Customer Engagement and Its Impact on Brand Loyalty in Caring Colours Cosmetics, Martha Tilaar [PDF]

, 2016
The purpose of this research was to determine the influence of social media marketing against customer engagement and its impact on brand loyalty. Methods applied is a quantitative method by distributing questionnaire to 100 customers.
Gunawan, A. (Annetta), Muchardie, B. G. (Brian), Yudiana, N. H. (Nabila)   +2 more
core   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Strategies and effectiveness analysis of modern marketing methods: A comparative study based on influencer marketing and traditional advertising marketing [PDF]

SHS Web of Conferences
This study examines the evolution of advertising from traditional media to social media platforms and analyzes how consumer engagement on different social media platforms impacts advertising effectiveness.
Liu Hongjie
doaj   +1 more source

Increasing customer equity through social media content and engagement

Entrepreneurial Business and Economics Review, 2023
Objective: The objective of the article is to investigate the impact of social media content on engagement and customer equity. The moderating role of the customer relationship is also analyzed.
Angga Febrian
doaj   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source