Results 31 to 40 of about 345,449 (267)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Jakten på gulatingstedet

open access: yesTidsskrift for Kulturforskning, 2021
The debate about the localisation of the medieval legal assembly Gulating has been going for almost 200 years. Collection, publication and discussion of historical legends (historiske sagn) has been an important aspect of this discussion.
Audun Kjus
doaj  

Social Memory and the Role of the Hippocampal CA2 Region

open access: yesFrontiers in Behavioral Neuroscience, 2019
The CA2 region of the hippocampus is a somewhat obscure area lacking in an understanding of its form and function. Until recently, the CA2 has been thought of as merely an extension of the CA3, with some referring to it as the CA3a region.
Nikolaos Tzakis, Matthew R. Holahan
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

TOPLUMSAL HAFIZANIN SİYASAL ALAN TARAFINDAN İNŞA SÜRECİNİN SOSYAL BİLGİLER/TARİH DERS KİTAPLARINA YANSIMALARI

open access: yesTurkish History Education Journal, 2019
Sosyal bilimlerin çalışma alanlarında giderek dikkat çeken ve disiplinler arası bir çalışma alanı olarak şekillenen toplumsal hafıza, siyasal yapılar tarafından beden, mekân, tarih ve dil politikalarıyla inşa edilmektedir.
Mustafa İÇEN, Gül TUNCEL
doaj   +1 more source

Russian youth about the Great Patriotic War and family as spiritual imperatives of Russian civil society

open access: yesНаука. Культура. Общество, 2020
The article deals with the problems of reproduction of social memory and the mechanism of continuity of spiritual and moral values in the context of everyday family relations "parents-children".
Boris S. Pavlov   +3 more
doaj   +1 more source

Social Memory through Posthumous Remembrance

open access: yes, 2022
The chapter humanises the souls of two departed individuals that were very close to ...
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Digital Engagement: Personality Is The Context Of The Text

open access: yesProceedings from the Document Academy, 2015
This paper examines digital-technology as a tool and an environment with the individuals’ personality at the intersection of the two: Its impact on social memory and the unbound document.
Diane Spencer-Scarr
doaj   +1 more source

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