Results 11 to 20 of about 359,891 (263)

Nicotinamide riboside supplementation corrects deficits in oxytocin, sociability and anxiety of CD157 mutants in a mouse model of autism spectrum disorder

Scientific Reports, 2020
Oxytocin (OT) is a critical molecule for social recognition and memory that mediates social and emotional behaviours. In addition, OT acts as an anxiolytic factor and is released during stress. Based on the activity of CD38 as an enzyme that produces the
Maria Gerasimenko, Stanislav M. Cherepanov, Kazumi Furuhara, Olga Lopatina, Alla B. Salmina, Anna A. Shabalova, Chiharu Tsuji, Shigeru Yokoyama, Katsuhiko Ishihara, Charles Brenner, Haruhiro Higashida   +10 more
doaj   +1 more source

Receptor for advanced glycation end-products and child neglect in mice: A possible link to postpartum depression

Comprehensive Psychoneuroendocrinology, 2022
The receptor for advanced glycation end-products (RAGE), a pattern recognition molecule, has a role in the remodeling of vascular endothelial cells mainly in lungs, kidney and brain under pathological conditions.
Haruhiro Higashida, Maria Gerasimenko, Yasuhiko Yamamoto   +2 more
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Virtual Dwelling and the Phenomenology of Experience: Museum Encounters between Self and World

Humanities, 2023
This article provides an anthropologically derived philosophy of the nature of experience in relation to the lifeworld of virtual tourism. Framed around Martin Heidegger and Tim Ingold’s concept of dwelling, I interrogate what the implications of a ...
Catherine Palmer
doaj   +1 more source

Destination memory: Memory associated with social interactions

Frontiers in Psychology, 2023
Within the field of memory research, studies on destination memory (e.g., the ability to remember to whom information was previously told) show how it is closely associated with social cognition. The present review thus summarizes the literature on destination memory and demonstrates how it involves social interaction. It offers a comprehensive picture
Mohamad El Haj, Mohamad El Haj, Mohamad El Haj   +2 more
openaire   +4 more sources

One Single Nucleotide Polymorphism of the TRPM2 Channel Gene Identified as a Risk Factor in Bipolar Disorder Associates with Autism Spectrum Disorder in a Japanese Population

Diseases, 2020
The transient receptor potential melastatin 2 (TRPM2) is a non-specific cation channel, resulting in Ca2+ influx at warm temperatures from 34 °C to 47 °C, thus including the body temperature range in mammals.
Naila Al Mahmuda, Shigeru Yokoyama, Toshio Munesue, Kenshi Hayashi, Kunimasa Yagi, Chiharu Tsuji, Haruhiro Higashida   +6 more
doaj   +1 more source

Evidence for superior encoding of detailed visual memories in deaf signers

Scientific Reports, 2022
Recent evidence shows that deaf signers outperform hearing non-signers in some tests of visual attention and discrimination. Furthermore, they can retain visual information better over short periods, i.e., seconds. However, it is unknown if deaf signers’
Michael Craig, Michaela Dewar, Graham Turner, Trudi Collier, Narinder Kapur   +4 more
doaj   +1 more source

Selegiline Ameliorates Depression-Like Behavior in Mice Lacking the CD157/BST1 Gene, a Risk Factor for Parkinson’s Disease

Frontiers in Behavioral Neuroscience, 2017
Parkinson’s disease (PD), a neurodegenerative disorder, is accompanied by various non-motor symptoms including depression and anxiety, which may precede the onset of motor symptoms. Selegiline is an irreversible monoamine oxidase-B (MAO-B) inhibitor, and
Satoka Kasai, Satoka Kasai, Toru Yoshihara, Toru Yoshihara, Olga Lopatina, Katsuhiko Ishihara, Haruhiro Higashida   +6 more
doaj   +1 more source

Intestinal transepithelial permeability of oxytocin into the blood is dependent on the receptor for advanced glycation end products in mice

Scientific Reports, 2017
Plasma oxytocin (OT) originates from secretion from the pituitary gland into the circulation and from absorption of OT in mother’s milk into the blood via intestinal permeability.
Haruhiro Higashida, Kazumi Furuhara, Agnes-Mikiko Yamauchi, Kisaburo Deguchi, Ai Harashima, Seiichi Munesue, Olga Lopatina, Maria Gerasimenko, Alla B. Salmina, Jia-Sheng Zhang, Hikari Kodama, Hironori Kuroda, Chiharu Tsuji, Satoshi Suto, Hiroshi Yamamoto, Yasuhiko Yamamoto   +15 more
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CD38, CD157, and RAGE as Molecular Determinants for Social Behavior

Cells, 2019
Recent studies provide evidence to support that cluster of differentiation 38 (CD38) and CD157 meaningfully act in the brain as neuroregulators. They primarily affect social behaviors. Social behaviors are impaired in Cd38 and Cd157 knockout mice. Single-
Haruhiro Higashida, Minako Hashii, Yukie Tanaka, Shigeru Matsukawa, Yoshihiro Higuchi, Ryosuke Gabata, Makoto Tsubomoto, Noriko Seishima, Mitsuyo Teramachi, Taiki Kamijima, Tsuyoshi Hattori, Osamu Hori, Chiharu Tsuji, Stanislav M. Cherepanov, Anna A. Shabalova, Maria Gerasimenko, Kana Minami, Shigeru Yokoyama, Sei-ichi Munesue, Ai Harashima, Yasuhiko Yamamoto, Alla B. Salmina, Olga Lopatina   +22 more
doaj   +1 more source

Android Robot-Mediated Mock Job Interview Sessions for Young Adults with Autism Spectrum Disorder: A Pilot Study

Frontiers in Psychiatry, 2017
The feasibility and preliminary efficacy of an android robot-mediated mock job interview training in terms of both bolstering self-confidence and reducing biological levels of stress in comparison to a psycho-educational approach human interview was ...
Hirokazu Kumazaki, Zachary Warren, Blythe A. Corbett, Yuichiro Yoshikawa, Yuichiro Yoshikawa, Yoshio Matsumoto, Haruhiro Higashida, Teruko Yuhi, Takashi Ikeda, Hiroshi Ishiguro, Hiroshi Ishiguro, Mitsuru Kikuchi   +11 more
doaj   +1 more source