Results 41 to 50 of about 359,891 (263)
Ability within disability: Reflective memories shared with Dr Kasturi Varley
HTS Teologiese Studies/Theological Studies, 2022 In a post-apartheid South Africa, the value of reflective memories and their impact on community history gives credibility to their relationship with personal struggles such as disability, be it physical or political.
Kogielam K. Archary, Christina Landman
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Etnoantropološki Problemi, 2016 Along with many different definitions of archaeology, from the inception of the discipline to the present, it may be valid to assert that it is a kind of complex dialogue on heritage with the public of contemporary societies.
Ivan Vranić
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Stress amplifies memory for social hierarchy [PDF]
Frontiers in Neuroscience, 2007 Individuals differ in their social status and societies in the extent of social status differences among their members. There is great interest in understanding the key factors that contribute to the establishment of social dominance structures. Given that stress can affect behavior and cognition, we hypothesized that, given equal opportunities to ...
Cordero, MI, Sandi, C
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Contested Rites – Janša’s Politics of Statehood Celebration in Contemporary Slovenia
Łódzkie Studia Etnograficzne, 2019 Political division, which re-emerged after Slovenian independence and parliamentary democracy in 1991, has strongly influenced Slovenian social life.
Peter Simonič
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Collective Memory, Social Psychology of [PDF]
, 2015 info:eu-repo/semantics ...
Licata, Laurent, Mercy, Aurelie
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