Results 81 to 90 of about 222,824 (299)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Social Urban Metabolism Strategies (SUMS) for Cities

open access: yes, 2016
The city is where important exchanges of resources occur, but where what is received from the environment differs greatly from what is returned to it. Energy, water, materials and food are received, yet other waste energy, wastewater, waste materials and
Polit, D. Jácome   +2 more
core   +2 more sources

Why Catalonia will see its energy metabolism increase in the near future: an application of MuSIASEM [PDF]

open access: yes
This paper applies the so-called Multi-Scale Integrated Analysis of Societal and Ecosystem Metabolism (MuSIASEM) to the economy of the Spanish region of Catalonia. By applying Georgescu-Roegen’s fund-flow model, it arrives at the conclusion that within a
J. Ramos-Martin, S. Cañellas-Bolta
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Multi-Scale Integrated Analysis of Societal and Ecosystem Metabolism (MUSIASEM): An Outline of Rationale and Theory [PDF]

open access: yes
This paper presents an outline of rationale and theory of the MuSIASEM scheme (Multi-Scale Integrated Analysis of Societal and Ecosystem Metabolism).
Kozo Mayumi   +2 more
core  

Intracellular Acetyl Unit Transport in Fungal Carbon Metabolism [PDF]

open access: yes, 2010
Acetyl coenzyme A (acetyl-CoA) is a central metabolite in carbon and energy metabolism. Because of its amphiphilic nature and bulkiness, acetyl-CoA cannot readily traverse biological membranes.
Distel, B.   +5 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Intelligent technology-driven diabetes prevention and control: From informatization management to artificial intelligence

open access: yesScience Progress
The escalating prevalence of diabetes, along with its complications and mortality risks, imposes a substantial disease burden worldwide. The current suboptimal medical conditions and poor self-management among diabetic patients have exacerbated the ...
Geer Deng, Wang Chengshi
doaj   +1 more source

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