Results 91 to 100 of about 8,580,127 (353)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Racism, Ideology, and Social Movements
, 2017 Racism, sexism, and other forms of injustice are more than just bad attitudes; after all, such injustice involves unfair distributions of goods and resources. But attitudes play a role. How central is that role?
S. Haslanger
semanticscholar +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Des « mouvements émotionnels » à la mobilisation des émotions
Terrains/Théories, 2014 The development of victim activism provided an opportunity to study the role of emotions in collective action a recent field of research on social movements. Indeed, sociologists as Walgrave and Verlhust characterize victims movements as “new emotional
Stéphane Latté
doaj +1 more source
Social Movements: Organizations and Organizing
, 2017 We discuss two lines of research that emerged at the crossroads of social movement studies and organization theory, focusing on organizations and organizing, respectively. We speak of ‘organizations’ and ‘organizing’ to emphasize that the ‘social movement/organizations’ nexus is distinct from the ‘social movement/organizing’ nexus.
de Bakker, Frank +2 more
openaire +4 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Editorial: Socio-psychological perspectives on collective behavior and social movements. [PDF]
Front Psychol, 2023 Oyanedel JC +3 more
europepmc +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
The effect of social movements on COVID-19 case increases and death in Turkey. [PDF]
Clin Epidemiol Glob Health, 2023 Gun MA, Hanci O.
europepmc +1 more source