Results 81 to 90 of about 1,380,152 (244)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Making Change: How Social Movements Work and How to Support Them [PDF]
, 2009 Provides guidance for funders and activists on funding and sustaining a successful social movement. Details key elements of success, organizational capacities that need to be developed, areas for effective foundation investment, and issues to ...
Manuel Pastor, Rhonda Ortiz
core
Toward a social psychophysics of face communication [PDF]
, 2017 As a highly social species, humans are equipped with a powerful tool for social communication—the face, which can elicit multiple social perceptions in others due to the rich and complex variations of its movements, morphology, and complexion ...
Jack, Rachael E., Schyns, Philippe G.
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Social Movements in Southeast Sulawesi, 1906-1942
Humaniora, 2012 The social movement in period of 1906-1942 started with the intervention of the Dutch colonial government to the economic income resources of the people which then triggered social chaos and unrest marked by open conflict and opposition between the ...
La Ode Rabani
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
E-politics from the citizens’ perspective. The role of social networking tools in influencing citizens [PDF]
, 2018 The progress of civilization, supported by the development of new technologies, has led to a series of social, economic and political changes. The information society, in its expectations and through access to knowledge, has significantly affected a ...
Kapsa, Izabela
core +2 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Des « mouvements émotionnels » à la mobilisation des émotions
Terrains/Théories, 2014 The development of victim activism provided an opportunity to study the role of emotions in collective action a recent field of research on social movements. Indeed, sociologists as Walgrave and Verlhust characterize victims movements as “new emotional
Stéphane Latté
doaj +1 more source