Results 61 to 70 of about 195,111 (266)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Social Movements: Organizations and Organizing
, 2017 We discuss two lines of research that emerged at the crossroads of social movement studies and organization theory, focusing on organizations and organizing, respectively. We speak of ‘organizations’ and ‘organizing’ to emphasize that the ‘social movement/organizations’ nexus is distinct from the ‘social movement/organizing’ nexus.
de Bakker, Frank +2 more
openaire +4 more sources
Social Movements in Southeast Sulawesi, 1906-1942
Humaniora, 2012 The social movement in period of 1906-1942 started with the intervention of the Dutch colonial government to the economic income resources of the people which then triggered social chaos and unrest marked by open conflict and opposition between the ...
La Ode Rabani
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Des « mouvements émotionnels » à la mobilisation des émotions
Terrains/Théories, 2014 The development of victim activism provided an opportunity to study the role of emotions in collective action a recent field of research on social movements. Indeed, sociologists as Walgrave and Verlhust characterize victims movements as “new emotional
Stéphane Latté
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Editorial: Socio-psychological perspectives on collective behavior and social movements. [PDF]
Front Psychol, 2023 Oyanedel JC +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source