Results 61 to 70 of about 1,380,152 (244)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Social movements in sustainability transitions : identity, social learning & power in the Spanish & Turkish water domains / [PDF]

open access: yes, 2010
Descripció del recurs: el 02 de novembre de 2010Dominant economic growth and nation-state building practices are often based on detaching individuals from other individuals and communities from their natural environment in which their livelihoods used to
Ilhan, Akgün   +1 more
core   +1 more source

Political Homophily in Independence Movements: Analysing and Classifying Social Media Users by National Identity [PDF]

open access: yes, 2018
Social media and data mining are increasingly being used to analyse political and societal issues. Here we undertake the classification of social media users as supporting or opposing ongoing independence movements in their territories.
Liakata, Maria   +3 more
core   +4 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Agroecological Formación in Rural Social Movements

open access: yesRadical Teacher, 2014
Among the many sectors currently engaged in struggle against the corporate food system, small farmers play a particularly important role—not only do they constitute a legitimate alternative to global agribusiness, but also they are the heirs to long ...
Nils McCune, Juan Reardon, Peter Rosset
doaj   +1 more source

'OK Boomer': Internet Memes as Consciousness Building

open access: yesRadical Teacher, 2020
While the role of the internet and social media in influencing political organizing has gained the attention of scholars in recent years, less attention has been paid to the social influence of internet memes specifically.
Morgan Anderson, Gabriel Keehn
doaj   +1 more source

Mutual-Excitation of Cryptocurrency Market Returns and Social Media Topics [PDF]

open access: yes, 2018
Cryptocurrencies have recently experienced a new wave of price volatility and interest; activity within social media communities relating to cryptocurrencies has increased significantly.
Gorse, Denise, Phillips, Ross C.
core   +1 more source

State marionettes, phantom organisations or genuine movements? [PDF]

open access: yes, 2014
Of all the rural social movements in the world, those in post-socialist Russia have been considered to be among the weakest. Nevertheless, triggered by the neo-liberal reforms in the countryside, state attention to agriculture and rising land conflicts ...
Mamonova, N.V. (Natalia)   +1 more
core   +4 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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