Results 71 to 80 of about 8,580,127 (353)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
'OK Boomer': Internet Memes as Consciousness Building
Radical Teacher, 2020 While the role of the internet and social media in influencing political organizing has gained the attention of scholars in recent years, less attention has been paid to the social influence of internet memes specifically.
Morgan Anderson, Gabriel Keehn
doaj +1 more source
The UltraS: An Emerging Social Movement? [PDF]
Review of European Studies, 2009 In recent years, there has been a rise in the conflict between the Italian police forces and football fans. This situation is a result of the resurgence of the UltraS (the S capital is a neologism of this study to suggest neo-fascist oriented fans' and to differentiate them from the wider hardcore football supporters -ultra’).
openaire +5 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Agroecological Formación in Rural Social Movements
Radical Teacher, 2014 Among the many sectors currently engaged in struggle against the corporate food system, small farmers play a particularly important role—not only do they constitute a legitimate alternative to global agribusiness, but also they are the heirs to long ...
Nils McCune, Juan Reardon, Peter Rosset
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
The Media Commons and Social Movements
Chasqui, 2019 La década que inició en 2010 despertó con agitaciones sociales en metrópolis como Nueva York o El Cairo; pero también en sitios periféricos y sin embargo neurálgicos como Chile, donde un movimiento que demandaba educación accesible para todos se gestó ...
Rubén Huerta
doaj +1 more source