Results 101 to 110 of about 8,985,407 (374)
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
Social Movement Literature and U.S. Labour: A Reassessment
Largely due to its conservative profile at the time, the U.S. labour movement was largely absent from modern social movement literature as it developed in response to the new social movements of the 1960s and 1970s.
Keith Mann
doaj
Agroecological Formación in Rural Social Movements
Among the many sectors currently engaged in struggle against the corporate food system, small farmers play a particularly important role—not only do they constitute a legitimate alternative to global agribusiness, but also they are the heirs to long ...
Nils McCune, Juan Reardon, Peter Rosset
doaj +1 more source
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair+17 more
wiley +1 more source
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser+11 more
wiley +1 more source
Mutual-Excitation of Cryptocurrency Market Returns and Social Media Topics [PDF]
Cryptocurrencies have recently experienced a new wave of price volatility and interest; activity within social media communities relating to cryptocurrencies has increased significantly.
Gorse, Denise, Phillips, Ross C.
core +1 more source
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source
Social Movements in Southeast Sulawesi, 1906-1942
The social movement in period of 1906-1942 started with the intervention of the Dutch colonial government to the economic income resources of the people which then triggered social chaos and unrest marked by open conflict and opposition between the ...
La Ode Rabani
doaj +1 more source
SOCIAL CHANGE THROUGH SOCIAL MOVEMENTS [PDF]
poster abstractThrough studying the interworkings of social movements and how they alter the perceptions of the mainstream society this study looks to investigate how social movements create social change.
Taylor, Alexis C.
core