Results 101 to 110 of about 1,449,664 (357)

Lipdubs as an Instrument to Overcome Invisibility in the Mass-Media. A study of four enthusiastic cases recorded in Quebec, USA, Catalonia and the Basque Country [PDF]

open access: yes, 2012
This paper summarizes the principal conclusions of an investigation into lipdub as an instrument used by social movements in order to get more social influence. Since its creation in 2006, the phenomenon of lipdubs has increased\ud considerably.
de la Piscina, Txema Ramirez
core  

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Issues in the study of virtual world social movements [PDF]

open access: yes, 2011
Virtual worlds are online three-dimensional worlds that are often constructed to look much like the real world. As more people begin to use these virtual worlds, virtual communities are emerging enabling various social activities and social interactions ...
Gardner, L, Mckenna, Brad, Myers, M
core   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee   +9 more
wiley   +1 more source

The public sphere and network democracy: Social movements and political change? [PDF]

open access: yes, 2015
The article critically examines the democratic possibilities of technological innovations associated with Web 2.0 tools and in this context it address the first and second ‘waves’ of academic debates concerning the social media and the public sphere in ...
Iosifidis, P., Wheeler, M.
core  

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

open access: yesMolecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella   +18 more
wiley   +1 more source

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