Results 61 to 70 of about 1,556,388 (313)
Many Hands, More Impact: Philanthropy's Role in Supporting Movements [PDF]
, 2013 GEO has prepared a publication that provides a framework for understanding the array of roles that funders can play in supporting movements and networks.
core
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Law, Social Movements, and the Political Economy of Domestic Violence [PDF]
, 2013 This article uses the occasion of the 2013 Reauthorization of the Violence Against Women Act (VAWA) to review the circumstances by which legal theory and social movement discourse have circumscribed the scope of VAWA and the dominant approach to domestic
Weissman, Deborah M.
core +2 more sources
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
The Media Commons and Social Movements
Chasqui, 2019 La década que inició en 2010 despertó con agitaciones sociales en metrópolis como Nueva York o El Cairo; pero también en sitios periféricos y sin embargo neurálgicos como Chile, donde un movimiento que demandaba educación accesible para todos se gestó ...
Rubén Huerta
doaj +1 more source
Political Homophily in Independence Movements: Analysing and Classifying Social Media Users by National Identity [PDF]
, 2018 Social media and data mining are increasingly being used to analyse political and societal issues. Here we undertake the classification of social media users as supporting or opposing ongoing independence movements in their territories.
Liakata, Maria +3 more
core +4 more sources
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source