Results 101 to 110 of about 1,094,585 (248)

Social network sites (SNS) an archetype of techno-social stress: A systematic review

Heliyon
Background: Social Networking Sites (SNS) are widely used platforms known for both their hedonic and social connectivity benefits. Although there is considerable interest in understanding how personal technostress affects individual well-being, a ...
January F. Naga, Ryan A. Ebardo
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Visual interpersonal communication on social network sites in romantic relationships

Journal of Digital Social Research
Based on a research project examining visual communication in close relationships in Switzerland, this study examines interpersonal communication between romantic partners on social network sites (SNSs).
Federico Lucchesi, Katharina Lobinger
doaj   +1 more source

Ubiquitous Social Networks: Opportunities and Challenges for Privacy-Aware User Modelling [PDF]

Privacy has been recognized as an important topic in the Internet for a long time, and technological developments in the area of privacy tools are ongoing. However, their focus was mainly on the individual. With the proliferation of social network sites,
Bettina Berendt, Bettina Hoser, Seda Gürses, Sören Preibusch   +3 more
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Ethical Dilemmas About Social Network Sites – A View From Romania

Проблеми на постмодерността
In contemporary society, the ubiquity of technology has led, somewhat inevitably, to a series of theoretical and practical concerns related to the problems caused by the security of personal data in an interconnected world.
Valentina Marinescu
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Young People’s Socialization and Identity Construction Processes in Social Networks: The Case of Facebook / Sosyal Paylaşım Ağlarında Gençlerin Sosyalleşme ve Kimlik İnşası Süreçleri: Facebook Örneği [PDF]

Folklor/Edebiyat, 2015
Today, the number of individuals who allocate an important part of their time for social networks has increased and these networks have become more frequently visited virtual platforms together with the effect of new downsized media tools.
Tuba Sütlüoğlu2
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Exploring subjective well-being in social network sites? - Supplementary fit and social support perspective

MATEC Web of Conferences, 2016
This study formed a framework theorized on supplementary fit and social support to explore users’ perceptions of Subject Well-Being in Social Network Sites. Online surveys were conducted in Facebook and Google+.
Liu Ying Chieh, Chen Hung Yi, Yao Bo Yen
doaj   +1 more source