Results 81 to 90 of about 148,159 (258)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

The effect of social network sites usage in climate change awareness in Latin America. [PDF]

Popul Environ, 2023
Gómez-Casillas A, Gómez Márquez V.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Visual interpersonal communication on social network sites in romantic relationships

Journal of Digital Social Research
Based on a research project examining visual communication in close relationships in Switzerland, this study examines interpersonal communication between romantic partners on social network sites (SNSs).
Federico Lucchesi, Katharina Lobinger
doaj   +1 more source

Social network sites as learning environments and their implications for mental health. [PDF]

Front Digit Health, 2022
Hussenoeder FS.
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Ethical Dilemmas About Social Network Sites – A View From Romania

Проблеми на постмодерността
In contemporary society, the ubiquity of technology has led, somewhat inevitably, to a series of theoretical and practical concerns related to the problems caused by the security of personal data in an interconnected world.
Valentina Marinescu
doaj   +1 more source

Motivation Scale for Using Social Network Sites: Comparative Study between Facebook, Instagram, Twitter, Snapchat and LinkedIn. [PDF]

Psychol Belg, 2023
Masciantonio A, Bourguignon D.
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Young People’s Socialization and Identity Construction Processes in Social Networks: The Case of Facebook / Sosyal Paylaşım Ağlarında Gençlerin Sosyalleşme ve Kimlik İnşası Süreçleri: Facebook Örneği [PDF]

Folklor/Edebiyat, 2015
Today, the number of individuals who allocate an important part of their time for social networks has increased and these networks have become more frequently visited virtual platforms together with the effect of new downsized media tools.
Tuba Sütlüoğlu2
doaj