Results 81 to 90 of about 148,473 (256)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Visual interpersonal communication on social network sites in romantic relationships

open access: yesJournal of Digital Social Research
Based on a research project examining visual communication in close relationships in Switzerland, this study examines interpersonal communication between romantic partners on social network sites (SNSs).
Federico Lucchesi, Katharina Lobinger
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Ethical Dilemmas About Social Network Sites – A View From Romania

open access: yesПроблеми на постмодерността
In contemporary society, the ubiquity of technology has led, somewhat inevitably, to a series of theoretical and practical concerns related to the problems caused by the security of personal data in an interconnected world.
Valentina Marinescu
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Young People’s Socialization and Identity Construction Processes in Social Networks: The Case of Facebook / Sosyal Paylaşım Ağlarında Gençlerin Sosyalleşme ve Kimlik İnşası Süreçleri: Facebook Örneği [PDF]

open access: yesFolklor/Edebiyat, 2015
Today, the number of individuals who allocate an important part of their time for social networks has increased and these networks have become more frequently visited virtual platforms together with the effect of new downsized media tools.
Tuba Sütlüoğlu2
doaj  

Exploring subjective well-being in social network sites? - Supplementary fit and social support perspective

open access: yesMATEC Web of Conferences, 2016
This study formed a framework theorized on supplementary fit and social support to explore users’ perceptions of Subject Well-Being in Social Network Sites. Online surveys were conducted in Facebook and Google+.
Liu Ying Chieh, Chen Hung Yi, Yao Bo Yen
doaj   +1 more source

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