Results 71 to 80 of about 1,238,486 (291)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Consumer social network brand identification and personal branding. How do social network users choose among brand sites?

open access: yesCogent Business & Management, 2017
Brands’ social networking sites (fan pages) are increasingly attracting the attention of scientists and managers intrigued by their potential application for brand value creation.
Wioleta Kucharska
doaj   +1 more source

Teens, Social Media, and Privacy [PDF]

open access: yes, 2013
Teens share a wide range of information about themselves on social media sites; indeed the sites themselves are designed to encourage the sharing of information and the expansion of networks.
Aaron Smith   +6 more
core  

Social Ranking Techniques for the Web

open access: yes, 2013
The proliferation of social media has the potential for changing the structure and organization of the web. In the past, scientists have looked at the web as a large connected component to understand how the topology of hyperlinks correlates with the ...
Banerjee A.   +6 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Online Social Network Sites Usage and Impression Management of Adolescents and Relationship with Emotional and Behavioral Problems

open access: yesPsychiatry and Behavioral Sciences, 2020
Objective: In recent years, almost all youths go online on social network sites (SNSs) practically every day. Online social networks may be considered a connection between the inner lives of adolescents and the outside world.
Hatice Gozde Akkin Gurbuz   +3 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

A social network analysis of supportive interactions on prenatal sites

open access: yesDigital Health, 2016
Objective The purpose of this exploratory study was to validate and extend previous research on social support by identifying which dimensions of social support are most commonly exchanged on health-related social networking sites and how social network ...
Heather J. Hether   +2 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

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