Results 101 to 110 of about 1,238,486 (291)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Cancer 2.0: A Summary of Recent Research [PDF]

open access: yes, 2010
Outlines findings on Internet access and use among cancer patients compared with other chronic disease patients, the demand for health information online, the role of social network sites, and implications for cancer treatment and ...
Susannah Fox
core  

Latent Space Model for Multi-Modal Social Data

open access: yes, 2015
With the emergence of social networking services, researchers enjoy the increasing availability of large-scale heterogenous datasets capturing online user interactions and behaviors.
Al Zamal F.   +9 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Young people, social media, social network sites and sexual health communication in Australia: ‘this is funny, you should watch it [PDF]

open access: yes, 2013
Social media and social network sites (SNS) are an evolving area for sexual health communication with young people. They present opportunities and challenges for sexual health professionals and young people alike, such as learning through interactivity ...
Albury, Kath   +3 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Visual interpersonal communication on social network sites in romantic relationships

open access: yesJournal of Digital Social Research
Based on a research project examining visual communication in close relationships in Switzerland, this study examines interpersonal communication between romantic partners on social network sites (SNSs).
Federico Lucchesi, Katharina Lobinger
doaj   +1 more source

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