Results 101 to 110 of about 490,883 (317)

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Risks and Threats of Social Networks Communication

open access: yesCommunications, 2014
This paper focuses on social networks as a source of information and a tool for its sharing. The first part of the paper defines the theoretical background while the second part is devoted to the evaluation of research which was conducted among ...
Jan Zavodny Pospisil, Lucie Sara Zavodna
doaj   +1 more source

Dynamics of Social Networks

open access: yesProcedia - Social and Behavioral Sciences, 2011
AbstractIn the past decade Social Network Analysis (SNA) has become an established research field in the social and behavioral sciences as well as the natural sciences. The international conference on Applications of Social Network Analysis (ASNA) brings this interdisciplinary community together to assess the state of the field and discuss current ...
openaire   +3 more sources

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Attempted suicide in social networks. [PDF]

open access: bronze, 1969
Norman Kreitman, P Smith, Eng-Seong Tan
openalex   +1 more source

Social networks and the firm

open access: yesRevista de Administração, 2016
Individuals often base their decisions on what they observe in their neighborhood or peer groups. It can be, on the one hand, that individuals gather information from their peers’ experiences: for example, a consumer will be more likely to adopt a given product if many of that consumer’s friends report a positive experience with the product.
Goyal, Sanjeev, Gagnon, Julien
openaire   +4 more sources

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

open access: yesMolecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo   +8 more
wiley   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

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