Results 111 to 120 of about 7,335,104 (302)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Finding Influential Users in Social Media Using Association Rule Learning

open access: yes, 2016
Influential users play an important role in online social networks since users tend to have an impact on one other. Therefore, the proposed work analyzes users and their behavior in order to identify influential users and predict user participation ...
Anton Borg   +14 more
core   +2 more sources

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Six Keynote Papers on Consciousness with some Comments on their Social Implications: TSC Conference, Hong Kong, 10-14 June 2009 [PDF]

open access: yes, 2010
Six keynote papers presented at TSC 2009 — by Susan Greenfield, Wolf Singer, Stuart Hameroff, Jonathan Schooler, Hakwan Lau, and David Chalmers—are reviewed below in order to investigate to what extent social analysis can be
Whitehead, Charles
core  

Institutional Order, Interaction Order and Social Order: Administering Welfare, Disciplining the Poor

open access: yesPolitiche Sociali, 2019
In his famous 1982 address as a president of the American Sociological Association, Erving Goffman returns to the relation between the interaction order and social structures, which he defines as a 'loose coupling'. This paper elaborates on this intriguing but partially disappointing response, and proposes to complement it by analyzing the role of ...
openaire   +2 more sources

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Everyday Interaction as Collective Performance: Towards a Theory of Implicit Synchronization

open access: yesСоциология власти
The purpose of this article is to propose the concept of synchronization as a minimal temporal quantum of social interactions. For this, the author turns to the sociological concepts of synchronization and places them on the "macro/micro" continuum.
Viktoriia V. Pogudina Pogudina
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Coalition formation under power relations [PDF]

open access: yes
We analyze the structure of a society driven by power relations. Our model has an exogenous power relation over the set of coalitions of agents. Agents determine the social order by forming coalitions.
Piccione, Michele, Razin, Ronny
core   +1 more source

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