Results 51 to 60 of about 7,335,104 (302)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Social support and recovery in acute respiratory distress syndrome survivors: a prospective cohort study

ERJ Open Research
Background Social support (SS) may contribute to the long-term recovery of critical illness survivors. This study focuses on survivors of acute respiratory distress syndrome (ARDS) to investigate the causal relationship between SS and health-related ...
Hermann Szymczak, Susanne Brandstetter, Sebastian Blecha, Frank Dodoo-Schittko, Magdalena Rohr, Thomas Bein, Christian Apfelbacher   +6 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Legitimacy and procedural justice in prisons [PDF]

, 2010
All social situations are ‘ordered’ in some way, comprising a constantly changing set of relationships that establish the structure within which human action occurs.
Bradford, Ben, Jackson, Jonathan, Shiner, Mike, Taylor, Dominic, Tyler, Tom R.   +4 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Reconstructing the Common Good: Theology and the Social Order [PDF]

, 1995
Reviewed Book: Dorrien, Gary J. Reconstructing the Common Good: Theology and the Social Order.
Cole-Arnal, Oscar
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Food Allergy Diagnosis in Early Childhood: Journey Mapping Study With Parents and Pediatricians

Clinical and Translational Allergy
Food allergy (FA) in early childhood can be challenging for families, even before a diagnosis is made, as parents often experience anxiety and have to change their routines.
Madlen Hörold, Magdalena Rohr, Christian Apfelbacher, Susanne Brandstetter   +3 more
doaj   +1 more source

The Crime of Barrocolorado: A History of Emotions, Anarchism, Medicine, and Crime in Early Twentieth-Century Colombia

Latin American Research Review
This article explores contemporary discourses of deviation in early twentieth-century Colombia. Through analysis of a presidential assassination attempt in 1906, known as the Crime of Barrocolorado, it discusses the social construction of notions of ...
Daniel Humberto Trujillo Martínez
doaj   +1 more source

Social Entrepreneurship That Truly Benefits the Poor: An Integrative Justice Approach [PDF]

, 2013
The phenomenal growth of social entrepreneurship over thelast decade has ably demonstrated how technology, innovation, and anentrepreneurial spirit can afford better solutions to the vexing social andenvironmental problems of our time than can ...
Santos, Nicholas J. C.
core   +3 more sources