Results 71 to 80 of about 1,876,704 (311)

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Strengthening the LGUS, municipal fisheries, and the MFARMCS in San Miguel Bay : final report

open access: yes, 2007
The project entitled “Strengthening the LGUs and MFARMCs in San Miguel Bay” is an action-research facilitated by a grant from the International Institute of Rural Reconstruction conducted from April to December 2006.
Institute of Social Order
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Other Titles: Biennial Report of the Division of Social Welfare, 1960-1972 Division of Social Welfare (1960-1970)

open access: yes, 1960
These biennial reports are summaries of the activities of this agency. They were extracted from a series of Kansas agency reports covering over 100 state agencies and institutions bound together for each biennium, 1959/1960 - 1979/1980.
Kansas. State Department of Social Welfare.
core  

Legal Order Founded on Human Wisdom [PDF]

open access: yesAnnals of Philosophy, Social and Human Disciplines, 2015
In the present work I approach a topic of great complexity, always anchored in social actuality because it addresses to an extremely sensitive area in which law is intertwined with the human wisdom.
Elena IFTIME
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Organisation

open access: yes, 2017
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/62462The
Institute Of Social Order
core  

Social media in the language classrooms: maximizing students' Higher Order Thinking Skills (HOTS) [PDF]

open access: yes, 2023
Technology has proliferated and has become prominent in the education world over the past few years. Technology has become a way not only to meet the learner's needs but also to address digital literacy emphasis in 21st-century skills.
Drs Nasrul, Muhammad Amrullah   +4 more
core  

«Social order» as the mechanism of political positioning of big business

open access: yesПутеводитель предпринимателя, 2020
The article presents an analysis of social order, which is considered to be a mechanism of political participation of big business and solution of social problems.
A. V. Kapkina
doaj  

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