Results 81 to 90 of about 13,578,919 (257)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Impact of the First Wave of the COVID-19 Pandemic on New Applications for Long-term Care Insurance in a Metropolitan Area of Japan

Journal of Epidemiology, 2021
Satoshi Seino, Yu Nofuji, Yuri Yokoyama, Yui Tomine, Mariko Nishi, Toshiki Hata, Shoji Shinkai, Yoshinori Fujiwara, Akihiko Kitamura   +8 more
doaj   +1 more source

Design and development of serious games for future proof peatland management: Option for virtual Living Labs [PDF]

E3S Web of Conferences
Worldwide, including Indonesia and the EU, current (agricultural) use in peatlands is based on massive water drainage. Because drainage leads to environmental problems, many scholars, policy makers and (agricultural) entrepreneurs are rethinking peatland
Witteveen Loes, Roosmini Dwina, Mansoor Alvanov, van der Maas Peter, Mahmud, Horsten Brechtje, Blankestijn Wouter, Verspui Walter, Iriana Windy, Fliervoet Jan   +9 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

„… I try to focus on the gender discrimination aspect, but among disabled people that’s not the main problem” — Barriers and supporting factors in the participation of students with disabilities in higher education

Fogyatékosság és Társadalom
The article examines visible and invisible structural barriers and biases impeding access to higher education, offering examples from Hungary and beyond.
Sándor, Anikó, Fazekas-Vinkovits, Ágnes Sarolta, Kovács, Krisztina, Könczei, György   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

“You are Needed and You Exist”: Motivation for Social Participation of Older Activists, Rostov Oblast, Russia [PDF]

Received 27 October 2023. Accepted 11 March 2024. Published online 5 April 2024.The article aims to identify the sociological approach’s perspective on the reasons behind the continued social engagement of older individuals.
Kienko, T. S.
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Using social media to widen young people’s participation in social work education: final report for Nominettrust [PDF]

, 2014
Using a systematic review approach, this study set out to identify social media resources currently used by service users to share knowledge and experience, in order that they could be used to widen young people’s participation in social work education ...
Coren, E., Hossain, R., Franklin, P.
core  

Child welfare services’ investigation of violence against children in Norway – a pilot and feasibility study

Nordic Social Work Research
This pilot and feasibility study includes seven child welfare services (CWS) that completed a total of 136 surveys. The research design, initially developed and conducted in Sweden, is aimed at increasing knowledge about violence against children within ...
Rakel Aasheim Greve, Tone Hee Åker, Karl Ove Hufthammer, Kjersti Alsaker, Birgitta Persdotter   +4 more
doaj   +1 more source