Results 101 to 110 of about 1,251,629 (312)

Allies Not Adversaries: Teaching Collaboration to the Next Generation of Doctors and Lawyers to Address Social Inequality [PDF]

, 2008
Recent reports from the Carnegie Foundation for the Advancement of Teaching, as well as from other medical and legal educators, stress that professional training of doctors and lawyers focuses too narrowly on knowledge-based learning, and not enough on ...
Tyler, Elizabeth Tobin
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Breastfeeding experience, barriers, and facilitators among mothers of vulnerable low birth weight infants in Amhara region, Ethiopia: a qualitative exploratory study

International Breastfeeding Journal
Background Globally, 15 − 20% of all live births are low birthweight (LBW) newborns, and many mothers with LBW newborns experience feeding difficulties.
Moses Collins Ekwueme, Yihenew Alemu Tesfaye, Heran Biza, Mulusew Lijalem Belew, Meseret Asefa, Destaw Asnakew, Abebe Gebremariam Gobezayehu, John Cranmer, Melissa Fox Young   +8 more
doaj   +1 more source

Integrating assessments of secure tenure rights and co-management for small-scale fisheries in seafood sustainability ratings systems: two new scoring methods for FishSource's sustainability assessments

Frontiers in Sustainable Food Systems
Market-based approaches to seafood sustainability have gained popularity in the last decade. Market-based tools, such as certification and ratings systems, enable seafood companies along supply chains to engage in sustainability initiatives while ...
Hugh Govan, Enrique Alonso-Población, Susana Segurado, Rolando Labraña-Cornejo, Pedro Ferreiro-Velasco, Miguel Andreu-Cazenave   +5 more
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Politics and Social Partnership - Flexible Network Governance [PDF]

This paper reassesses the relationship between social partnership and the broader Irish policy process. What has developed may be conceptualised as “flexible network governance”.
Niamh Hardiman
core  

Century Services Year I Evaluation Report on the Social Business Enterprise Model [PDF]

, 2001
The Mid-America Institute on Poverty is conducting a three year (12/30/1999 - 12/30/2002) evaluation of Century Services employment activities and social business enterprise model.
Amy Rynell, Paul Makarewicz
core  

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Regional Security through Synergistic Integration: A Euro-Mediterranean Regional Security Complex? Jean Monnet/Robert Schuman Paper Series Vol. 5, No. 13 June 2008 [PDF]

, 2008
In this paper I argue that the recent Iraq war shows that there are, at least with respect to the Greater Middle East, no “quick fixes” for regional security, but that the painstaking process of political, economic and social development and ...
Boening, Astrid B.
core  

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source