Results 101 to 110 of about 1,248,042 (313)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Breastfeeding experience, barriers, and facilitators among mothers of vulnerable low birth weight infants in Amhara region, Ethiopia: a qualitative exploratory study

International Breastfeeding Journal
Background Globally, 15 − 20% of all live births are low birthweight (LBW) newborns, and many mothers with LBW newborns experience feeding difficulties.
Moses Collins Ekwueme, Yihenew Alemu Tesfaye, Heran Biza, Mulusew Lijalem Belew, Meseret Asefa, Destaw Asnakew, Abebe Gebremariam Gobezayehu, John Cranmer, Melissa Fox Young   +8 more
doaj   +1 more source

Integrating assessments of secure tenure rights and co-management for small-scale fisheries in seafood sustainability ratings systems: two new scoring methods for FishSource's sustainability assessments

Frontiers in Sustainable Food Systems
Market-based approaches to seafood sustainability have gained popularity in the last decade. Market-based tools, such as certification and ratings systems, enable seafood companies along supply chains to engage in sustainability initiatives while ...
Hugh Govan, Enrique Alonso-Población, Susana Segurado, Rolando Labraña-Cornejo, Pedro Ferreiro-Velasco, Miguel Andreu-Cazenave   +5 more
doaj   +1 more source

Conclusion: Uncertain Outcomes of Conflict and Negotiation [PDF]

, 1997
[Excerpt] To elaborate on each of these points, the findings presented in this book can be summarized as follows. First of all, the German model, that is, a social partnership approach to the negotiation of terms and conditions for the organization of an
Turner, Lowell
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Politics and Social Partnership - Flexible Network Governance [PDF]

This paper reassesses the relationship between social partnership and the broader Irish policy process. What has developed may be conceptualised as “flexible network governance”.
Niamh Hardiman
core  

Regional Security through Synergistic Integration: A Euro-Mediterranean Regional Security Complex? Jean Monnet/Robert Schuman Paper Series Vol. 5, No. 13 June 2008 [PDF]

, 2008
In this paper I argue that the recent Iraq war shows that there are, at least with respect to the Greater Middle East, no “quick fixes” for regional security, but that the painstaking process of political, economic and social development and ...
Boening, Astrid B.
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Institutsiyne providing of social partnership [PDF]

, 2009
В статті розглянуті формування та розвиток інституційного забезпечення діяльності соціальних партнерів, визначено пріоритетні напрямки його вдосконалення на найближчу перспективу.
Kolosok, A. M., Колосок, Андрій Мирославович   +1 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source