Results 51 to 60 of about 1,264,953 (363)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Re-Audit of Adherence to Antipsychotic Prescribing Guidelines in a Psychiatric Unit for Older Adult Females: Evaluating Improvements and Compliance Post-Interventions

BJPsych Open
Aims: The aim of this audit was to assess adherence to antipsychotic prescribing guidelines in one of the Older Adults Female wards at Kent and Medway NHS and Social Care Partnership Trust (KMPT).
Maria Moisan, Daisy Carroll, Ayebatonye Ajiteru   +2 more
doaj   +1 more source

Whose outcomes are they anyway? Report of the pilot evaluation of a joint service\ud [PDF]

, 2011
Health and social care partnership working is often predicated on the notion that it improves outcomes for service users. Yet there is a lack of evidence linking partnerships to changes in outcomes. Against this background, the Health Services Management
Dickinson, Helen, Glasby, Jon, McCarthy,, Linda, Miller, Robin   +3 more
core  

Local status and power in area-based health improvement partnerships [PDF]

, 2014
This is the authors' PDF version of an article published in Health© 2014. The definitive version is available at http://hea.sagepub.comArea-based initiatives (ABIs) have formed an important part of public policy towards more socio-economically deprived ...
Bartlett D, Berkeley D, Bradford N, Carlisle S, Charmaz K, Department for Communities and Local Government, Department of Health, Department of Health, Elias N, Elias N, Elias N, Elias N, Elias N, Elias N, Lawless P, National Institute for Health and Clinical Excellence, Pawson R, Stewart M, Strauss AL, Unwin J, Yin RK   +20 more
core   +4 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Assessing Adherence to Antipsychotic Prescribing and Monitoring Guidelines in a Psychiatric Unit for Older Adult Females in Kent and Medway NHS and Social Care Partnership Trust (KMPT): A Retrospective Audit

BJPsych Open
Aims Antipsychotic medications are commonly used in the management of psychiatric disorders, including in older adults. However, the use of these medications in older adults can be associated with a higher risk of adverse effects such as cardiovascular ...
Maria Moisan, Bianca Dixon, Ayebatonye Ajiteru   +2 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Challenges and Delay in Treatment With Clozapine Due to Thrombocytopenia: A Case Study

BJPsych Open
Aims Clozapine is the most effective antipsychotic medication for patients with treatment-resistant psychotic disorders. Its discontinuation can precipitate relapse that can be often challenging to treat.
Suresh Thapaliya, Glenda Boutell, Mudasir Firdosi   +2 more
doaj   +1 more source

CONTROL OF ALCOHOL CONSUMPTION IN THE COUNTRIES OF NORTHERN DIMENSION PARTNERSHIP IN PUBLIC HEALTH ABD SOCIAL WELL­BEING

Кардиоваскулярная терапия и профилактика, 2018
Alcohol consumption is one of the causes of premature death from the main non­communicable diseases (NCD), such as cardiovascular diseases, malignancies, diabetes. In the countries of Northern Dimension Partnership in Public Health and Social Well­being (
R. G. Oganov, G. Ya. Maslennikova, A. E. Imaeva   +2 more
doaj   +1 more source

Social Partnership in Germany: Lessons for U.S. Labor and Management [PDF]

, 1993
German industrial relations in the postwar period have made a major contribution to German industrial success. The German system is rooted in the explicit recognition of well organized interests: strong, assertive employers and employers\u27 associations
Turner, Lowell
core   +1 more source