Results 61 to 70 of about 1,264,953 (363)

Self-awareness and reflection: exploring the 'therapeutic use of self' [PDF]

open access: yes, 2005
Assesses what the participants gained from a pilot partnership course set up to help social care staff to explore new therapeutic ways of working with people with learning disabilities.
Kwaitek, Elaine   +2 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Collaborative Funding for Greater Impact: A Case Study of the Cincinnati Experience: Lessons Learned From the Social Innovation Fund [PDF]

open access: yes, 2012
Offers guidance on grantmaker collaboratives from the city's experience with the Strive Partnership and Cincinnati/Northern Kentucky Social Innovation Fund, including the need for a unifying vision, clear expectations, and maximum funder ...

core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Understanding the Care Home Psychiatric Service in North Kent

open access: yesBJPsych Open
Aims: Over 300,000 people in England and Wales reside in care home settings, with a large proportion of these people thought to have memory difficulties.
Emily Pettifor, Mohan Bhat
doaj   +1 more source

Social Partnership: An Organizing Concept for Industrial Relations Reform [PDF]

open access: yes, 1994
[Excerpt] In this era of globalization and intensified world market competition, once stable relationships involving firms, unions and government have come under pressure everywhere.
Turner, Lowell
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Procyclidine Use in Long-Acting Injectable Antipsychotics

open access: yesBJPsych Open
Aims: Following a Serious Untoward Incident investigation into a patient death where blood tests revealed procyclidine overdose, significant concerns emerged regarding procyclidine prescribing practices.
Shalina Mitchell, Prabin Gautam
doaj   +1 more source

Evolution of an academic-public library parthership [PDF]

open access: yes, 2016
A partnership to improve access to health information via an urban public library system was established in St. Louis, Missouri, in 2011. A multiyear project was outlined that included an information needs assessment, a training class for public library ...
Anwuri, Victoria V   +13 more
core   +3 more sources

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