Results 81 to 90 of about 1,251,629 (312)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Readmission Patterns to KMPT Acute Wards

BJPsych Open
Aims: To identify patterns of readmission to acute wards and look for specific themes associated with readmissions – discharge planning, diagnosis, gender, social support, accommodation issues and any other associations.
Olubunmi Olure, Valsraj Koravangattu
doaj   +1 more source

A community-based health-social partnership program for community-dwelling older adults: a hybrid effectiveness-implementation pilot study. [PDF]

BMC Geriatr, 2022
Wong AKC, Wong FKY, Wong MCS, Chow KKS, Kwan DKS, Lau DYS.   +5 more
europepmc   +1 more source

Problem statement of modeling the congruence of social partnership participants' interests based on agency approach [PDF]

, 2015
The article deals with the peculiarities of institutional regulation of social and labor relations in the country by using the multi agent approach. All members of labor market have been presented as economic agent.
Sybirtsev, Volodymyr, Сибірцев, В. В.   +1 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

STAMP (Supporting Treatment and Appropriate Medication in Paediatrics) to STOMP (Stopping Over Medication of People With a Learning Disability and Autistic People) – A Review of the Demographic and Clinical Characteristics of Transitions From CAMHS to Adult MHLD and Their Outcomes

BJPsych Open
Aims: This study investigates the demographic and clinical characteristics of young individuals (aged 17–24) transitioning from CAMHS (Child and Adolescent Mental Health Service) to Adult MHLD (Mental Health of Learning Disability) services in North Kent.
Sajitha Nair, Mogbeyiteren Eyeoyibo
doaj   +1 more source

Conclusion: Uncertain Outcomes of Conflict and Negotiation [PDF]

, 1997
[Excerpt] To elaborate on each of these points, the findings presented in this book can be summarized as follows. First of all, the German model, that is, a social partnership approach to the negotiation of terms and conditions for the organization of an
Turner, Lowell
core   +1 more source

Child Welfare Partnership for Research and Training: A Title IV-E University/Community Collaborative Research Model [PDF]

, 2013
University-community partnerships are increasingly recognized as valuable in educating students for professional practice and bridging the gap between research and practice.
D\u27Andrade, Amy, Donoviel, Brett, Drabble, Laurie, Le, Julia, Lemon, Kathy   +4 more
core   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

A Service Evaluation of Clinicians Writing Clinic Letters to Patients

BJPsych Open
Aims Writing clinic letters addressed and directed to the patient could be considered part of a strategy to implement a person-centred approach by giving patients more autonomy and understanding of their assessment and care plan. We carried out an audit
Elizabeth Junaid, Mogbeyiteren Eyeoyibo
doaj   +1 more source