Results 41 to 50 of about 241,303 (259)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Social Preferences Under Uncertainty [PDF]
SSRN Electronic Journal, 2013 Willingness to take risk depends on whether the risk affects others as well as oneself and on how the risk affects one's position vis-`a-vis others. Taking a bet can improve one's position relative to others or threaten it. We present an experiment that explores individual attitudes to lotteries that involve both oneself and another subject ...
openaire +3 more sources
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Ethics in Progress, 2015 This paper describes using current literature and research a problem that has plagued social scientists for centuries, see that of „moral sentiments?. Human beings are inherently social by nature and hold certain regard for others?
Jerome Nikolai Warren
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
LandThis article presents a spatial analysis of projects selected by city residents and implemented in five successive editions (2015–2019) of the participatory budgeting in Częstochowa, Poland.
Katarzyna Groszek +3 more
doaj +1 more source
Objective Status, Subjective Status and Prosociality of Swiss Apprentices
Swiss Journal of Sociology, 2019 In previous research, both positive and negative relationships between social status and prosociality have been reported. We argue that the nature of the observed status can explain these divergent findings.
Liebe Ulf +2 more
doaj +1 more source
Social Preferences and Context Sensitivity
Games, 2017 This paper is a partial review of the literature on ‘social preferences'. There are empirical findings that convincingly demonstrate the existence of social preferences, but there are also studies that indicate their fragility.
Jelle de Boer
doaj +1 more source
Eye‐tracking Social Preferences
Journal of Behavioral Decision Making, 2015 AbstractWe hypothesize that if people are motivated by a particular social preference, then choosing in accordance with this preference will lead to an identifiable pattern of eye movements. We track eye movements while subjects make choices in simple three‐person distribution experiments.
Jiang, Ting +2 more
openaire +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source