Results 81 to 90 of about 336,006 (300)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Do social preferences matter in competitive markets? [PDF]
Experimental evidence stresses the importance of so–called social preferences for understanding economic behavior. Social preferences are defined over the entire allocation in a given economic environment, and not just over one’s own consumption as is ...
Paul Heidhues, Frank Riedel
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Neural responses to advantageous and disadvantageous inequity
Frontiers in Human Neuroscience, 2012 In this paper we study neural responses to inequitable distributions of rewards despite equal performance. We specifically focus on differences between advantageous (AI) and disadvantageous inequity (DI).
Klaus eFliessbach +13 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Do social preferences matter in competitive markets?
, 2007 Heidhues P, Riedel F. Do social preferences matter in competitive markets?. Working Papers. Institute of Mathematical Economics. Vol 392. Bielefeld: Universität Bielefeld; 2007.Experimental evidence stresses the importance of so-called social preferences
Riedel, Frank ; https://orcid.org/ +1 more
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Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
, 2019 This data forms part of a ESRC-Centre for Population Change scholarship project on the stated preferences of carers of older people in Scotland. The purpose of the project is to better understand the factors that may be involved in the decision to use ...
Thomas, Nadine
core
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
Endogenous Social Preferences, Heterogeneity and Cooperation [PDF]
We set up an analytical framework focusing on the problem of interaction over time when economic agents are characterized by various types of distributional social preferences.
Zarri, Luca
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