Results 51 to 60 of about 5,776,008 (313)

Hete-CF: Social-Based Collaborative Filtering Recommendation using Heterogeneous Relations

open access: yes, 2014
Collaborative filtering algorithms haven been widely used in recommender systems. However, they often suffer from the data sparsity and cold start problems.
Luo, Chen, Pang, Wei, Wang, Zhe
core   +2 more sources

Parameterized Algorithmics for Computational Social Choice: Nine Research Challenges [PDF]

open access: yes, 2014
Computational Social Choice is an interdisciplinary research area involving Economics, Political Science, and Social Science on the one side, and Mathematics and Computer Science (including Artificial Intelligence and Multiagent Systems) on the other ...
Bredereck, Robert   +5 more
core   +3 more sources

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf   +10 more
wiley   +1 more source

Russia, China: Poverty Alleviation (Comparative Analysis)

open access: yesУправленческое консультирование, 2020
Goal and objectives. The article analyzes the state policy of Russia and China on poverty alleviation, conducted a comparative analysis of the strategy of the two countries in solving the problem, basic areas, social programs, measures, measures of ...
I. S. Orlova, G. M. Tsinchenko
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Civilized Death: The Issue of Stray Animals and Sports Mega- Events in Russia

open access: yesГалактика медиа: журнал медиа исследований, 2023
The article examines how the strategy of constructing the social problem of animal cruelty in Russia has become successful in the context of preparing and holding sports mega- events. The constructionist theory of social problems by M.
Vera Galindabaeva
doaj   +1 more source

Institutional conditions and social innovations in emerging economies: insights from Mexican enterprises’ initiatives for protecting/preventing the effect of violent events [PDF]

open access: yes, 2020
Latin-American countries are characterised by societal problems like violence, crime, corruption, the informality that influence any entrepreneurial activity developed by individuals/organisations. Social innovations literature confront “wicked problems”
Guerrero, Maribel, Urbano, David
core   +2 more sources

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

open access: yesMolecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa   +14 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Teaching Python with team‐based learning: using cloud‐based notebooks for interactive coding education

open access: yesFEBS Open Bio, EarlyView.
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley   +1 more source

Home - About - Disclaimer - Privacy