Results 71 to 80 of about 421,015 (257)

THE ANALYSIS OF SOCIAL PROTECTION EXPENDITURE OF ROMANIA BY FUNCTIONS ACCORDING TO THE EUROPEAN UNION METHODOLOGY [PDF]

open access: yesAnnals of the University of Petrosani: Economics, 2014
For Romania, the status of full member of the European Union created obligations, but especially the need to respect the directives and regulations of the European bodies.
OANA DOBRE-BARON
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Breaking the Sitting Cycle: Albania’s School-Based Movement Revolution

open access: yesBaltic Journal of Sport and Health Sciences
The “Active Classrooms Albania” initiative was launched to reduce sedentary time and promote physical activity among primary school students, addressing rising levels of childhood obesity and physical inactivity.
Ketrin Zeno, Fiona Konomi, Klea Troka
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Quality of Life of Children from Families Affected by Migration: The Role of Educational Policies

open access: yesEducation Sciences
The problems of children from Romanian transnational families represent a current issue and one of great interest in the field of public policies that need to be developed in Romania in order to offer solutions that will lead to an increase in the ...
Aniela Matei, Mihaela Ghența
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Early Childhood Education and Care Services, and Parents’ Work–Life Balance

open access: yesEducation Sciences
Parents’ work–life balance represents a major challenge, especially for those who have young children. The present article aims to identify the perceptions of parents relating to the purpose of early childhood education and care (ECEC) services, care ...
Aniela Matei   +2 more
doaj   +1 more source

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