Results 61 to 70 of about 430,868 (306)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The mechanism of the social state and the place of the pension system in it: theoretical and legal aspects

open access: yesLaw and Safety
The article is devoted to the theoretical and legal study of the role and place of the pension system in the mechanism of the social state on the example of the modern Ukrainian legal experience.
S. S. Polesov
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Ex Interim Voting in Public Good Provision [PDF]

open access: yes
We report the results of an experimental study that compares voting mechanisms in the provision of public goods. Subjects can freely decide how much they want to contribute.
Sven Fischer, Andreas Nicklisch
core  

Social Services Provision in a Rural Area, 1976

open access: yes, 1980
copyright UK Data Service and data collection copyright owner.The aim of this survey was to examine the social welfare needs of persons living in a rural area and the effectiveness of services in relation to the particular enviroment.Main Topics ...
Hereford and Worcester County Council, Social Services Department   +1 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Social Innovation and Nonprofit Resource Provision: A Discourse Analysis

open access: yesCanadian Journal of Nonprofit and Social Economy Research
This research adopts a resource dependency approach to support the process of social innovation application within the context of nonprofit resource procurement using a comparative sample of re- source-providing organizations (n = 8) and nonprofit ...
Aaron Turpin, Micheal Shier
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Inequality, Group Cohesion, and Public Good Provision: An Experimental Analysis [PDF]

open access: yes
Recent studies argue that inequality reduces group cohesiveness and dampens support for expenditures on public goods and social programs. In light of competing theoretical explanations and mixed empirical evidence of the effect of inequality on public ...
Jeffrey Milyo   +2 more
core  

Information needed to cope with crisis in the lives of individuals and communities : an assessment of the roles public libraries and voluntary sector agencies play in the provision of such information [PDF]

open access: yes, 2004
Paper submitted for the PhD in Information Studies at the University of Sheffield for the Research Training Program modules. This paper discuss the provision of community information services as mean to help people in the communities to cope with their ...
Muela-Meza, Zapopan Martín
core  

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