Results 81 to 90 of about 430,868 (306)
Overcoming goal displacement and power displacement in social service provision
Scandinavian Journal of Disability Research, 2009 Disabled people in their encounters with social authorities often experience them as knowing better and of little help. Social service authorities often lose sight of their actual goal of assisting clients to have greater opportunities to participate in ...
Steen Bengtsson
doaj +1 more source
Why Praise Inequality? Public Good Provision, Income Distribution and Social Welfare [PDF]
We consider a two-person Cournot game of voluntary contributions to a public good with identical individual preferences, and examine equilibrium aggregate welfare under a separable, symmetric and concave social welfare function.
Indraneel Dasgupta
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Abstract There is a growing appreciation that social provisioning in the global south is closely shaped by politics, particularly in terms of the level of public expenditure that governments are willing to commit to sectors such as education and health.
Sam Hickey, Kunal Sen
openaire +1 more source
Public Provision of Private Child Goods [PDF]
This paper analyzes the public provision of private goods for children in a politicoeconomic model with endogenous fertility. The government provides every child with goods that can also be purchased by parents in private markets, and the level of ...
Daishin Yasui, Masako Kimura
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Public Health NutritionObjective: To explore the differences in social norms around parents’ food provision in different provision contexts and by demographics. Design: Qualitative study using story completion methodology via an online survey in September 2021.
Amelia G Scott +2 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source