Results 111 to 120 of about 136,465 (300)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Information systems benefit quantification
, 2009 This study shows basic and advanced methods of information systems benefit quantification and applies selected methods to a real life problem. The practical part has been used to justify an information systems investment of already implemented and future
Soukup, Václav
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On Social Knowledge and Its Empirical Investigation in Contemporary Organisations
Organizacijų Vadyba: Sisteminiai Tyrimai, 2019 The focus of knowledge management theories on codification and quantification and aspirations to manage knowledge in a similar manner to managing physical resources did not create a stable ground for knowledge management practices in organisations as was
Liubertė Irina
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Data and social science rhetoric: policy and instruction [PDF]
, 1996 journal articleI believe that social science and empirical investigation can make important contributions to our understanding and to resolution of policy issues, but only if we are clear on the nature of social science and the role of quantification. In
Jameson, Kenneth P.
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Quantification in Global Society
Petzke M. Quantification in Global Society. In: Verschraegen G, Vanderstraeten R, eds. Elgar Encyclopedia of Global Social Theory.
Petzke, Martin ; https://orcid.org/ +2 more
core +1 more source
The Social Costs of Automobility [PDF]
, 2010 The automobile is truly the most dominant mode of transport in Canada; a car is used by nearly 75% of the Canadian adult population each day. Under the auspices of sustainable development and practices, the impacts of automobile driving and its ...
Farber, Steven
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Ethical dimensions of quantification
, 2019 Wendy Espeland & Vincent Yung (2019) Social Science Information, Vol 58, 2, pp. 238-260 Abstract. The ethical dimensions of quantification are seldom analysed.
GdL
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