Results 41 to 50 of about 136,465 (300)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Quantification of Doughnut Economy with the Sustainability Window Method: Analysis of Development in Thailand

, 2021
The doughnut economy is a new approach for the inclusion of planetary boundaries and social foundation in the development of societies. The Sustainable Development Goals of the United Nations (UN) determine another view for development targets.
Jari Kaivo-oja, Jyrki Luukkanen, Jarmo Vehmas   +2 more
core   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

From social coding to economics of convention: a thirty-year perspective on the analysis of qualification and quantification investments [PDF]

, 2016
Among the contributions to the presently growing sociology of quantification, a long-standing French tradition has built on an approach to the "politics of statistics" based on the formatting practices of the transformative chain that leads to data.
Thévenot, Laurent
core   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Quantifying social distance using deep learning-based video analysis: results from the BTBR mouse model of autism

Frontiers in Behavioral Neuroscience
Autism spectrum disorder (ASD) is characterized by challenges in social communication, difficulties in understanding social cues, a tendency to perform repetitive behaviors, and restricted interests.
Tausif Khan, Tausif Khan, Kostiantyn Cherkas, Nikolas A. Francis, Nikolas A. Francis   +4 more
doaj   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Measurement of qualitative data, a trend in social research: The case of the school of accounting and administration, Cualiacan unit [PDF]

Ra Ximhai, 2012
The need to study the problems of social research from the new trends and paradigms more widespread and accepted today. The development of research techniques and analysis in search of objective criteria, quantification and coherence in social research ...
J. Bernardo Medina-Castillo, Lorenzo Manzanilla López de Llergo, Aurora Díaz   +2 more
doaj  

Social forest functions of reclaimed spoil heaps in the Ostrava-Karvina district

Journal of Forest Science, 2012
The functional efficiency of forest stands planted on the heaps originated by black coal mining was resolved in the territory of the Moravian-Silesian region. The aim was to verify the possibility of applying the method of Quantification of Social Forest
E. Lacková, P. Kupec, J. Polanská, B. Stalmachová   +3 more
doaj   +1 more source