Results 61 to 70 of about 136,465 (300)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

On Your Social Network De-anonymizablity: Quantification and Large Scale Evaluation with Seed Knowledge

open access: yes, 2015
—In this paper, we conduct the first comprehensive quantification on the perfect de-anonymizability and partial de-anonymizability of real world social networks with seed in-formation in general scenarios, where a social network can follow an arbitrary ...
Neil Zhenqiang Gong   +6 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Du capital social à la soutenabilité sociale : enseignements d’une démarche locale de construction d’indicateurs de bien-être soutenable

open access: yesDéveloppement Durable et Territoires, 2016
Based on the IBEST (“indicateurs de bien-être soutenable” in French) project, which focuses on the construction of sustainable territorial social indicators in the urban community of Grenoble, this article questions the operationality and the ...
Anne Le Roy, Fiona Ottaviani
doaj   +1 more source

MNSRQ: Mobile node social relationship quantification algorithm for data transmission in Internet of things

open access: yesIET Communications, 2021
The rapid development of the Internet of things has led to the explosive development of data in various fields. Traditional routing protocols cannot effectively handle the reception and transmission of data.
Yue Xu   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

QUANTITATIVE METHODS AND RESEARCH IN SOCIAL SCIENCE: LOGIC AND UTILITY OF THE USE OF QUANTIFICATION IN THE EXPLANATIONS OF SOCIAL PHENOMENA

open access: yesMediações: Revista de Ciências Sociais, 2013
The article presents a theoretical analysis on methodological foundations (not only procedural) of so-called "quantitative methods" in social science research, which are often – but mistakenly – reduced to the idea of "quantification techniques".
Marília Patta Ramos
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Quantification of shared air: a social and environmental determinant of airborne disease transmission.

open access: yesPLoS ONE, 2014
BackgroundTuberculosis is endemic in Cape Town, South Africa where a majority of the population become tuberculosis infected before adulthood. While social contact patterns impacting tuberculosis and other respiratory disease spread have been studied ...
Robin Wood   +7 more
doaj   +1 more source

Efficiency in Social Enterprises

open access: yesMultidisciplinary Journal for Education, Social and Technological Sciences, 2017
The aim of this article is to offer a review of the impact the different methodologies of analysis have on social enterprises, focusing the study on processes that establish a greater universality based on the degree of success achieved in their social ...
José Carlos Ballester-Miquel   +4 more
doaj   +1 more source

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