Results 131 to 140 of about 6,260,344 (295)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Understanding and Addressing Older Adults' Loneliness: The Social Relationship Expectations Framework. [PDF]

open access: yesPerspect Psychol Sci, 2023
Akhter-Khan SC   +4 more
europepmc   +1 more source

Sport, public relations and social media [PDF]

open access: yes, 2014
This chapter examines the disruptive nature of social media as it alters the relationship between sports journalism and public relations. It looks at some key examples and argues that while much is changing, some aspects of the relationship between the ...
Boyle, Raymond, Haynes, Richard
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Building a deeper understanding of social relationship health in adolescents with narcolepsy disorder. [PDF]

open access: yesJ Clin Sleep Med, 2023
Zhou ES   +5 more
europepmc   +1 more source

Use of Social Media in Presidential Campaigns: Do Social Media Have an Effect on the Political Behavior of Voters Aged 18-24? [PDF]

open access: yes, 2011
Today, the idea of social media is radically different from the media of a decade ago. While a decade ago the Internet was considered new media, our society now turns to Facebook, Twitter, and blogs as sources of information.
Hamilton, Samantha
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

The Strength of Association: Population Density and Social Deviance [PDF]

open access: yes, 2005
This issue is the second of three in Series 3a, "The Strength of Community-level Rates of Association," mapping Anchorage neighborhood characteristics by census block area, highlighting the correlation or lack of correlation between those characteristics
Justice Center, University of Alaska Anchorage
core  

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