Results 111 to 120 of about 6,260,344 (295)
Journal of Ageing and LongevityThis study examines the relationship between living arrangements and depressive symptoms among community-dwelling older adults in Japan, with a particular focus on gender differences.
Shinpei Ikeda +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Culture e Studi del Sociale, 2019 Emotions are essential elements that create social relationship: emotions are characterized by personal and social identity that come out from the communication with others. The social relationship’s construction is also emotional, in a mix of exogenous
Mariangela D'Ambrosio
doaj
The relationship between physical segregation and social marginalisation in the urban environment [PDF]
, 2005 This paper posits a relationship between the urban location of immigrant quarters and the likelihood that the inhabitants of such areas will improve themselves economically.
Vaughan, L
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Social Class and Concern for Climate Change in UNH College Students [PDF]
, 2016 This study explores the relationship between college students’ social class and level of concern for climate change. A survey was administered to 355 students at the University of New Hampshire, in the Fall of 2015.
Thompson, Charlotte
core +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Kenneth Gergen: "Old-Stream" Psychology Will Disappear With the Dinosaurs!
Forum: Qualitative Social Research, 2004 This conversation discusses the epistemology of social constructionism—theory, method, praxis—in relation with traditional psychology. The first part of the conversation deals with the places and forms of social constructionist thought and with the ...
Peter Mattes, Ernst Schraube
doaj
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source