Results 101 to 110 of about 340,207 (263)
The work presents a conceptual-theoretic framework for research on individual orientations among youth, a framework in which the results of the international project "Intemationales Lernen" on youth in five European countries will be interpreted.
Vjeran Katunarić +2 more
doaj
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Formação à informatica em Campinas: elementos e reflexões
Como formar à informática é problemática perseguida por pesquisadores e docentes na atualidade. O presente estudo teve por objetivos: a) avaliar o tipo de formação à informática oferecida por escolas especializadas em Campinas; b) explorar o espaço do ...
Eliana Martins da Silva Rosado
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
IMAGE" OF THE PAST AND PRESENT IN THE REPRESENTATIONS OF NIZHNY NOVGOROD
Awareness of the historical past, its evaluation and interpretation by society has important scientific value, as the identity of any nation begins with the history.
O. A. Nemova +2 more
doaj
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Establishing the fact of incapacity is both a legal and a clinical process, overseen by laws and professional standards that establish a requirement to consult with family and those closely connected to the individual whose capacities are being assessed.
Catherine Canuel +2 more
doaj
Social representation of fair price among professional photographers. [PDF]
Feybesse C +6 more
europepmc +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source

