Results 91 to 100 of about 11,088,270 (415)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Corporate social responsibility: a stages framework [PDF]

open access: yes, 2004
This article speculates whether British companies evolved more effective systems, practices, and procedures for implementing corporate social responsibility (CSR) and environmental policies within the period 1994-2004.
Carlisle, Ysanne M., Faulkner, David O.
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Effectiveness of non-medical health worker-led counselling on psychological distress: a randomized controlled trial in rural Nepal

open access: yesCambridge Prisms: Global Mental Health, 2019
Background.An essential strategy to increase coverage of psychosocial treatments globally is task shifting to non-medical counsellors, but evidence on its effectiveness is still scarce.
N. Markkula   +8 more
doaj   +1 more source

Corporate Social Responsibility [PDF]

open access: yes, 2019
This Element offers a thought-provoking and critical examination of corporate social responsibility (CSR). CSR has entered the boardroom and become a mainstream management concept for businesses to address their ethical, social and environmental responsibilities towards society.
Wickert, Christopher, Risi, David
openaire   +3 more sources

Corporate Social Responsibility Disclosure and Firm Financial Performance in Mining and Natural Resources Industry [PDF]

open access: yes, 2014
Business operations nowadays should not only pursue profits, but also contribute positively to the society as well as environment. This is because people currently have become more critical to the need of social control over the business.
Dayanti, N. (Nadia)   +1 more
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Analisis Corporate Social Responsibility (CSR) Subsektor Industri Energi di Indonesia dengan Pendekatan System Thinking [PDF]

open access: yes, 2015
Terlepas dari sudah adanya Undang-Undang yang mengatur Tanggung Jawab Sosial suatu Perusahaan, Perusahaan di Indonesia masih memiliki praktik Tanggung Jawab Sosial yang berbeda dalam terminologi kegiatan dan dampak yang diakibatkan.
Widaningrum, P. (Paramita)
core  

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