Results 91 to 100 of about 8,174,087 (362)

Corrigendum: Towards an understanding of global brain data governance: ethical positions that underpin global brain data governance discourse

Frontiers in Big Data, 2023
Paschal Ochang, Damian Eke, Bernd Carsten Stahl, Bernd Carsten Stahl   +3 more
doaj   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

The impact of social responsibility on corporate financial performance: A systematic literature review

Corporate Social Responsibility and Environmental Management, 2023
Rui Coelho, Shital Jayantilal, J. Ferreira   +2 more
semanticscholar   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Teleconsultation on patients with type 2 diabetes in the Brazilian public health system: a randomised, pragmatic, open-label, phase 2, non-inferiority trial (TELECONSULTA diabetes trial)Research in context

The Lancet Regional Health. Americas
Summary: Background: This study addresses the rising burden of type 2 diabetes mellitus, and explores the potential of teleconsultation, as an alternative for diabetes management. The primary objective was to test the hypothesis that teleconsultation is
Daniela Laranja Gomes Rodrigues, Gisele Silvestre Belber, Frederica Valle de Queiroz Padilha, Lucas Bassolli de Oliveira Alves, Álvaro Avezum, Marcos Aurélio Maeyama, Alexsandra Vitti, Greta Barriquel Pompermaier, Tanise Balvedi Damas, Mariana Selbach Selbach Otero, Raquel Souza de Aguiar, Renata Almeida de Andrade, Ligia Fonseca Spinel, Ana Paula Neves Marques Pinho, Haliton Alves de Oliveira Junior   +14 more
doaj  

"What does Closure even mean?" at Century Mine: Multiple companies, mine closure trajectories and disputation

Journal of Political Ecology
During the peak of its operation, Century mine, in Australia's western Queensland, was the third largest lead, zinc and silver mine in the world. The mine has had a turbulent history.
Alec Doomadgee, Sarah Elizabeth Holcombe
doaj   +2 more sources

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Charting neuroethics discourse in Africa: A scoping review of ethical issues of neuroscience research in Africa

IBRO Neuroscience Reports
The global neuroethics discourse has gained prominence since the beginning of the 21st century. Perspectives on neuroethics have been drawn from USA, Asia, the European Union etc.
Oluyinka Oyeniji, Kutoma Wakunuma, Adebowale Owoseni   +2 more
doaj  

Small modifier, big decision: switching to SUMO mode adds weight to cancer stemness in mammary tumors

Molecular Oncology, EarlyView.
Inhibition of protein SUMOylation has been shown to block tumorigenesis; however, the specific mechanisms by which SUMOylation controls the tumor‐initiating capacities remain elusive. Li et al. describe the role of Etv1 SUMOylation in cancer stem cells using mouse models of mammary gland tumorigenesis.
Veronika Yevdokimova, Yannick D. Benoit
wiley   +1 more source

Political control and journalist protests in Spanish public media in electoral campaigns: A decade of conflict

Etikk i Praksis: Nordic Journal of Applied Ethics, 2018
For thirteen consecutive years, Catalan public broadcasting journalists have protested against the so-called coverage quotas established by Spanish electoral regulations.
Carme Ferré-Pavia
doaj   +1 more source