Results 61 to 70 of about 2,929,136 (354)
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp+5 more
wiley +1 more source
Corporate Social Responsibility
Is shareholder interest in corporate social responsibility driven by pecuniary motives (abnormal rates of return) or nonpecuniary ones (willingness to sacrifice returns to address various firm externalities)? To answer this question, we summarize the literature by focusing on seven tests: ( a) costs of capital, ( b) performance of portfolios, ( c ...
Harrison G. Hong, Edward P. Shore
openaire +1 more source
Brucella NyxA and NyxB dimerization enhances effector function during infection
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre+4 more
wiley +1 more source
Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren+16 more
wiley +1 more source
Gauging the impact of community university engagement initiatives in India
Today, the world we live inis challenged with the co-existence of ‘prosperity and poverty’. In India, inparticular, although we are witnessing staggering increase in various economicindicators, our Human Development Indicators (HDIs) remain unenviable ...
Wafa Singh
doaj +1 more source
The concept of ‘social responsibility’ has first come into use with reference to the actors of economic activity and the various interests and needs of the stakeholders, i.e. the many individuals and organizations on which the actions of a company or a corporation have an impact.
openaire +3 more sources
Are Corporations Socially Responsible? Is Corporate Social Responsibility Desirable? [PDF]
extract] It is submitted that (for the reasons outlined in Part One) corporations have, at the most, only limited opportunities for pursuing CSR [corporate social responsibility]. Further (for the reasons outlined in Part Two), it is submitted that corporations should not engage in CSR.
openaire +2 more sources
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink+6 more
wiley +1 more source
Reasserting Gija women's role in mine site reclamation: A perspective from the Argyle Diamond Mine
The Argyle diamond mine, in the East Kimberley region of Western Australia, ceased production in late 2020 after 37 years of operations and producing 865 million carats of rough diamonds.
Kia Dowell, Sarah Elizabeth Holcombe
doaj +2 more sources