Results 61 to 70 of about 13,797,006 (300)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Economic, Social and Cultural Rights in Scotland
, 2015 This briefing paper examines the status of economic, social and cultural (ESC) rights in Scotland. The purpose of the paper is to provide a clear explanation of what we mean by 'ESC' rights, how they are currently protected in Scotland and how they might
Boyle, Katie
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Effective remedies & structural orders for social rights violations [PDF]
, 2022 This briefing document has been prepared for the Nuffield Foundation project on ‘Access to Justice For Social Rights: Addressing The Accountability Gap’, led by Dr. Katie Boyle.
Mukherjee, Gaurav
core
AJIL UnboundThe negotiations on a treaty to regulate global supply chains and their impact on human rights will hold its tenth session in December 2024. The question the negotiations address is not completely new: previous efforts, starting in the 1970s at the ...
Humberto Cantú Rivera
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Rights and liabilities for people with service animals
, 2003 Title from web page (viewed Nov. 24, 2004).; "Reviewed in 2003."; Harvested from the web on 11/24/04Ohio Legal Rights Service (OLRS) publication, Rights and Liabilities for People with Service ...
Ohio Legal Rights Service.
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
, 2006 Title from cover (i.e. p. [1]) of PDF document (viewed July 28, 2006).; "This publication was produced by Ohio Legal Rights Service through a contract with National Alliance on Mental Illness (NAMI) Ohio and with funding from the Ohio Department of ...
Ohio Legal Rights Service.
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source