Results 81 to 90 of about 3,546,996 (310)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Collective Bargaining as a Fundamental Right

open access: yesRevista de Direito Econômico e Socioambiental, 2017
This article has the purpose of analyzing collective bargaining as a fundamental right. This article starts from a conceptual analysis of collective labor conflicts, followed by a study of collective bargaining as a fundamental right, based on the 1988 ...
Gilberto Stürmer
doaj   +1 more source

Civil Rights 3.0 [PDF]

open access: yes, 2014
It is now commonplace to hear the LGBT rights movement being described as the last, or the next, or today’s, pre-eminent civil rights issue. This chapter will explore what that means from several perspectives: What does the label tell us about the civil ...
Hunter, Nan D.
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The Full-Belly Thesis: Should Economics Rights Take Priority Over Civil and Political Rights? Evidence from Sub-Saharan Africa [PDF]

open access: yes, 1983
This paper will discuss the relationship between civil/political and economic/social/cultural rights (as they are defined in the International Bill of Human Rights) in sub-Saharan Africa.
Howard-Hassmann, Rhoda E.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Young people and political action: who is taking responsibility for positive social change? [PDF]

open access: yes, 2004
A human rights perspective suggests that we are all responsible for ensuring the human rights of others, which in turn ensures that our own human rights are respected and protected.
Avery P   +15 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

(Dis)Embedded Women [PDF]

open access: yes, 2002
The central question we were asked to address in the Michigan Journal of International Law\u27s Symposium, Dueling Fates, was, Which international legal approach more effectively protects women\u27s rights, the collective or the individual?
Howard-Hassmann, Rhoda E.
core   +3 more sources

Women\u27s Social Rights: Untapped Economic Potential

open access: yes, 2015
This paper analyzes whether women’s social rights play a role in fostering higher levels of economic development. Prior development initiatives and economic policies failed to account for the productive capacities of women by discriminating against their
Evans, Monae S.
core  

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