Results 81 to 90 of about 13,797,006 (300)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Models of Incorporation and Justiciability for Economic, Social and Cultural Rights [PDF]

, 2018
First paragraph: The incorporation of international law into domestic law means embedding legal standards as set out in international law and making them enforceable at the domestic level. This incorporation can take many different forms.
Boyle, Katie
core  

Balancing Individual and Collective Rights: Implementation of Section 1.2 of The Canadian Human Rights Act [PDF]

, 2009
Implementation of section 1.2 of the Canadian Human Rights ...
Groves, Robert, Morse, Bradford, Vermette, D'Arcy   +2 more
core   +1 more source

Domestic human trafficking: invisible but essential to the governance of mobility, exploitation and sociopolitical belonging

Frontiers in Human Dynamics
Domestic human trafficking has been quietly present on anti-trafficking agendas without unsettling the dominant image of trafficking as a crime committed during or as an outcome of transnational migration processes.
Yelyzaveta Monastyrova
doaj   +1 more source

[Is information on social rights accessible to cancer patients?] [PDF]

Cad Saude Publica, 2023
Batista FG, Szklo AS.
europepmc   +1 more source

The Social Right to Property

Published
openaire   +2 more sources

The right to resettlement as a social right

, 2021
La necesidad de los derechos sociales en países emergentes es fundamental para el pleno desarrollo de la población en diferentes aspectos tanto económico, cultural, tecnológico, ambiental, social...etc. Según el artículo 1 de la constitución política del Perú la persona y su “dignidad” son el fin supremo de la sociedad y del Estado, y es en el caso de ...
openaire   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source