Results 81 to 90 of about 3,513,455 (311)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

The Relevance of the Concept of the Social Market Economy: Concluding Observations on the Contributions in this Special Issue

Utrecht Law Review, 2019
This article discusses the contributions of this Special Issue on the relationship between social and economic values and rights. It shows that the contributions are illustrative of the various ways in which the social market economy concept is, and ...
Frans Pennings
doaj   +1 more source

From industrial to digital citizenship: rethinking social rights in cyberspace. [PDF]

Theory Soc, 2023
Tomasello F.
europepmc   +1 more source

Human Rights Accountability Through Treaty Bodies: Examining Human Rights Treaty Monitoring for Water and Sanitation [PDF]

, 2015
Framing scholarship on human rights accountability through treaty bodies, this article examines the water and sanitation content of state human rights reporting to the United Nations Committee on Economic, Social and Cultural Rights.
Kim, Yuna, Meier, Benjamin Mason
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

[Is information on social rights accessible to cancer patients?] [PDF]

Cad Saude Publica, 2023
Batista FG, Szklo AS.
europepmc   +1 more source

Conditional citizens? welfare rights and responsibilities in the late 1990s [PDF]

, 1998
In Britain the relationship between welfare rights and responsibilities has undergone change. A new welfare 'consensus' that emphasizes a citizen ship centred on notions of duty rather than rights has been built.
Alcock, P., Alder, J., Beresford, P., Blair, T., Blair, T., Blunkett, D., C.P.A.G., Conservative Party, Conservative Party, D.E.T.R, Deacon, A., E.R.A.S., Etzioni, A., Field, F., Giddens, A., Gosling, P., Harman, H., Harman, H., Harman, H., Hetherington, P., Home Office, Hurd, D., Jeavans, C., Labour Party, Labour Party, Labour Party, Lister, R., Mann, K., Marshall, T.H., Meikle, J., Milne, S., N.H.F., Oliver, D., Peter Dwyer, Roche, M., Selbourne, D., Selbourne, D., Titmuss, R.M., Williams, F., Young, M.   +39 more
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

The European Pillar of Social Rights. Implementation and effects in the EU Member States [PDF]

Global Economic Observer, 2020
The article focuses on the research into the European Pillar of Social Rights, as well as the challenges of applying the basic principles in the Member States, in order to identify the best measures for their implementation in the European Community ...
ALINA LIGIA DUMITRESCU
doaj