Results 61 to 70 of about 224,782 (278)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

“Human – Social Robot” Interaction: Through Overcoming Barriers to Hybrid Communication

open access: yesДискурс, 2022
Introduction. The article analyzes the problems that arise during communication between a person and a social robot. Barriers that prevent a person from adapting to the specifics of communication tools embedded in the software of devices with artificial ...
V. I. Ignatyev, K. I. Spiridonova
doaj   +1 more source

Post-test questionnaire - HRI 1 [PDF]

open access: yes, 2018
This questionnaire has been used within the experiments described in a forthcoming publication in order to assess participants' conscious assessment of the quality of the interaction they have experienced with the robot. The questionnaire is based on two
Foerster, Frank
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Multimodal Signal Processing and Learning Aspects of Human-Robot Interaction for an Assistive Bathing Robot

open access: yes, 2017
We explore new aspects of assistive living on smart human-robot interaction (HRI) that involve automatic recognition and online validation of speech and gestures in a natural interface, providing social features for HRI.
Dometios, A. C.   +6 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Exploiting Child-Robot Aesthetic Interaction for a Social Robot

open access: yesInternational Journal of Advanced Robotic Systems, 2012
A social robot interacts and communicates with humans by using the embodied knowledge gained from interactions with its social environment. In recent years, emotion has emerged as a popular concept for designing social robots.
Jae-Joon Lee, Dae-Won Kim, Bo-Yeong Kang
doaj   +1 more source

Robots and Social Sustainability

open access: yes
Sustainability is no longer a matter of choice but is invariably linked to the survival of the entire ecosystem of our planet Earth. As robotics technology is growing at an exponential rate, it is crucial to examine its implications for sustainability. Our focus is on social sustainability, specifically analyzing the role of robotics technology in this
Indurkhya, Bipin, Sienkiewicz, Barbara
openaire   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Attitudes of Children with Autism towards Robots: An Exploratory Study [PDF]

open access: yes, 2018
In this exploratory study we assessed how attitudes of children with autism spectrum disorder (ASD) towards robots together with children's autism-related social impairments are linked to indicators of children's preference of an interaction with a robot
Charpiot, Louise   +3 more
core   +1 more source

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