Results 71 to 80 of about 7,989,963 (307)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Social capital and rural innovation process. The evaluation of the measure 124 \u201cCooperation for Development of New Products, Processes and Technologies in the Agriculture, Food and Forestry Sector\u201d in the Umbria Region (Italy) [PDF]

, 2016
The most recent theories on innovation point out the role of social networks, demonstrating how knowledge is intertwined with network communities and social capital represents an essential factor to comprehend innovation.
Cecchini, L., Da Re, R., Illuminati, R., Pisani, E., Torquati, B.   +4 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

SOCIAL CONFLICTS IN CHARITIES: REASONS, CONSEQUENCE SAND WAYS OF SOLVING THEM

Вестник университета, 2019
The article deals with the origin of social conflicts of international charities by addressing to a science of conflictology, it also emphasizes the difference between egoism and altruism related motivation of the parties involved into a charity process;
O. Andrienko
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

O mal-estar na representação: autoidentidade, esquizofrenia e a teatralidade do mundo social*

Sociedade e Estado
Resumo O artigo é parte de um programa de pesquisa em “heurística da insanidade”, o qual explora o poder analítico de ferramentas sociológicas na compreensão da esquizofrenia, assim como a relevância de investigações da experiência esquizofrênica para a ...
Gabriel Peters
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Homo sociologicus and the Society of Individuals

Historická sociologie, 2017
The present article follows the themes treated in “The Society of Individuals: How to Solve the Dilemma of Individualism and Holism in Historical Sociology” published in the journa Historická sociologie No. 1/2015.
Jiří Šubrt
doaj   +1 more source

The role of social interaction in farmers' climate adaptation choice [PDF]

, 2012
Adaptation to climate change might not always occur, with potentially\ud catastrophic results. Success depends on coordinated actions at both\ud governmental and individual levels (public and private adaptation).
Duinen, R. van, Filatova, T., Veen, A. van der   +2 more
core   +1 more source