Results 81 to 90 of about 2,524,397 (315)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

SOCIAL CONFLICTS IN CHARITIES: REASONS, CONSEQUENCE SAND WAYS OF SOLVING THEM

open access: yesВестник университета, 2019
The article deals with the origin of social conflicts of international charities by addressing to a science of conflictology, it also emphasizes the difference between egoism and altruism related motivation of the parties involved into a charity process;
O. Andrienko
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Hotel guests’ social commerce intention: The role of social support, social capital and social identification

open access: yes, 2020
Purpose The purpose of this paper is to synthesize a dyadic theoretical model which takes social-oriented and individual-initiative drivers into account and illustrates a mechanism between social commerce intention and its antecedents in the hospitality ...
Huang, GuoQiong Ivanka   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

International Social Survey Programme NL - ISSP-NL 2005-2006: Work Orientations / Role of Government

open access: yes, 2009
The modules 2005 (“Work Orientations”) and 2006 (“Role of Government”) of the International Social Survey Programme in the Netherlands [ISSP-NL] were conducted in 2006 as a stand-alone postal survey at the Free University Amsterdam [VUA] (Faculty of ...
Ganzeboom, H.B.G. (Vrije Universiteit, Amsterdam) DAI=info:eu-repo/dai/nl/070016992
core   +1 more source

O mal-estar na representação: autoidentidade, esquizofrenia e a teatralidade do mundo social*

open access: yesSociedade e Estado
Resumo O artigo é parte de um programa de pesquisa em “heurística da insanidade”, o qual explora o poder analítico de ferramentas sociológicas na compreensão da esquizofrenia, assim como a relevância de investigações da experiência esquizofrênica para a ...
Gabriel Peters
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Role of Social Capital and Social Value Creation in Augmenting Sustainable Performance of Social Enterprises: Moderating Role of Social Innovation

open access: yes, 2021
The last two decades represented the scarce discussion of the organizational social capital (SC) and its impact upon the social enterprises’ sustainable performance in the developing economies like Pakistan.
Abdul Majid   +3 more
core  

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