Results 91 to 100 of about 1,452,566 (223)

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini   +11 more
wiley   +1 more source

AI for social science and social science of AI: A Survey [PDF]

open access: yesarXiv
Recent advancements in artificial intelligence, particularly with the emergence of large language models (LLMs), have sparked a rethinking of artificial general intelligence possibilities. The increasing human-like capabilities of AI are also attracting attention in social science research, leading to various studies exploring the combination of these ...
arxiv  

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Characterizing SW-Efficiency in the Social Choice Domain [PDF]

open access: yesarXiv, 2015
Recently, Dogan, Dogan and Yildiz (2015) presented a new efficiency notion for the random assignment setting called SW (social welfare)-efficiency and characterized it. In this note, we generalize the characterization for the more general domain of randomized social choice.
arxiv  

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

Global AI Ethics: A Review of the Social Impacts and Ethical Implications of Artificial Intelligence [PDF]

open access: yesarXiv, 2019
The ethical implications and social impacts of artificial intelligence have become topics of compelling interest to industry, researchers in academia, and the public. However, current analyses of AI in a global context are biased toward perspectives held in the U.S., and limited by a lack of research, especially outside the U.S.
arxiv  

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Computer-Assisted Text Analysis for Social Science: Topic Models and Beyond [PDF]

open access: yesarXiv, 2018
Topic models are a family of statistical-based algorithms to summarize, explore and index large collections of text documents. After a decade of research led by computer scientists, topic models have spread to social science as a new generation of data-driven social scientists have searched for tools to explore large collections of unstructured text ...
arxiv  

The Deconstructive and Reconstructive Faces of Social Construction: An Interview with Ken Gergen

open access: yesForum: Qualitative Social Research, 2008
This conversation is an effort to include new elements in the FQS debate on constructionism. In his eloquent and unambiguous style GERGEN speaks out about critical realism, rationality, truth claims, grounding and other scientific and human beliefs ...
César A. Cisneros Puebla   +1 more
doaj  

Home - About - Disclaimer - Privacy