Results 51 to 60 of about 1,452,566 (223)

Bouso Freijo, Jesús (2013). El paquete estadístico R. CIS, Madrid

EMPIRIA: Revista de Metodología de Ciencias Sociales, 2014
El paquete estadístico R se está convirtiendo en un instrumento habitual tanto para las investigaciones como para la enseñanza de estadística de ciencias sociales.
Javier Callejo Gallego
doaj   +1 more source

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

FEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez, Cristina Velez‐delValle, Claudia Patricia Hernández‐Mosqueira, Walid Kuri‐Harcuch   +3 more
wiley   +1 more source

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

FEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring, Morten Roedgaard, Camilla Myrup Holst, Helene Christensen, Birgitta R. Knudsen, Lotte Bjergbaek, Anni Hangaard Andersen   +6 more
wiley   +1 more source

Towards the social media studies of science: social media metrics, present and future [PDF]

Bibliotecas. Anales de Investigacion. 2017. 13(1), 1-5, 2018
In this paper we aim at providing a general reflection around the present and future of social media metrics (or altmetrics) and how they could evolve into a new discipline focused on the study of the relationships and interactions between science and social media, in what could be seen as the social media studies of science.
arxiv  

Framing the Human Dimensions of Mountain Systems: Integrating Social Science Paradigms for a Global Network of Mountain Observatories

Mountain Research and Development, 2016
The Global Network of Mountain Observatories (GNOMO) is an international initiative seeking to increase communication and collaboration and align methodologies to assess commonalities and differences across the world's mountain landscapes.
Courtney G. Flint
doaj   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Machine learning in the social and health sciences [PDF]

arXiv, 2021
The uptake of machine learning (ML) approaches in the social and health sciences has been rather slow, and research using ML for social and health research questions remains fragmented. This may be due to the separate development of research in the computational/data versus social and health sciences as well as a lack of accessible overviews and ...
arxiv  

Enseñar Historia en la carrera de Nutrición

Clio y Asociados, 2018
The purpose of this paper is to describe and reflect on the importance of Social Sciences in the field of Medical Sciences, based on our experience in teaching Argentinean and Latino American History of Health Sciences in the National
Adrián Cammarota, Karina Faccia
doaj   +1 more source

Science and Social Knowledge or What We Do Not Know About What We Believe We Know

Studia Universitatis Babes-Bolyai Sociologia, 2023
What is knowledge and how can we analyse it from within social sciences as social knowledge? Our socially driven intuition tells us that knowledge is a special relation that humans have with their surrounding world.
Pasti Vladimir
doaj   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source